Hodgkin's lymphoma: Difference between revisions
Ostermayer (talk | contribs) (Text replacement - " pts" to " patients") |
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== Background == | ==Background == | ||
*Spreads from source lymph node to adjacent nodes | *Spreads from source lymph node to adjacent nodes | ||
*Bimodal distribution: young adulthood and older aged | *Bimodal distribution: young adulthood and older aged | ||
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*"B" symptoms: fever, night sweats, wt loss | *"B" symptoms: fever, night sweats, wt loss | ||
== Differential Diagnosis == | ==Differential Diagnosis == | ||
{{Cervical lymphadenopathy DDX}} | {{Cervical lymphadenopathy DDX}} | ||
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*LN biopsy | *LN biopsy | ||
== Treatment == | ==Treatment == | ||
*Manage acute complications | *Manage acute complications | ||
**Superior vena cava syndrome | **Superior vena cava syndrome | ||
Revision as of 11:32, 5 July 2016
Background
- Spreads from source lymph node to adjacent nodes
- Bimodal distribution: young adulthood and older aged
- Most common malignancy between ages of 15-19 yo
- Survival >90% in low-risk patients
Clinical Features
- Painless, firm, lymph node (usually cervical or supraclavicular)
- "B" symptoms: fever, night sweats, wt loss
Differential Diagnosis
Cervical Lymphadenopathy
- Hodgkin's lymphoma
- Non-Hodgkin's lymphoma
- Mononucleosis
- Toxoplasmosis
- Branchial cleft lesions
- Cat scratch disease
- Mycobacterial adenitis
Acute Leukemia/Lymphoma
Diagnosis
- CXR
- CT neck/C/A/P
- LN biopsy
Treatment
- Manage acute complications
- Superior vena cava syndrome
- Upper airway compression
- Do NOT give steroids