Neuroblastoma (peds): Difference between revisions
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**Spinal cord compression | **Spinal cord compression | ||
*Opsoclonus-myoclonus | *Opsoclonus-myoclonus | ||
**Highly | **Highly associated with neuroblastoma | ||
*Neutropenia/pancytopenia suggests bone marrow involvement | *Neutropenia/pancytopenia suggests bone marrow involvement | ||
Revision as of 08:57, 13 July 2016
Background
- Arises from primitive ganglion cells of sympathetic nervous system
- Most common neoplasm in 1st yr of life
- May arise anywhere along sympathetic nervous system
- Adrenal gland (40%)
- Abdomen (25%)
- Chest (15%)
Clinical Features
- Depends on location
- Large, painless abdominal mass
- Compression of bowel/bladder
- Horner syndrome
- Spinal cord compression
- Opsoclonus-myoclonus
- Highly associated with neuroblastoma
- Neutropenia/pancytopenia suggests bone marrow involvement
Differential Diagnosis
Diagnosis
- CXR
Management
- Admssion for tumor biopsy