Cyclospora: Difference between revisions

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==Signs/Symptoms==
==Signs/Symptoms==
*watery (sometimes explosive) diarrhea, loss of appetite, weight loss, stomach cramps/pain, bloating, increased flatus, nausea, and fatigue
*watery (sometimes explosive) [[diarrhea]], loss of appetite, weight loss, [[abdominal pain/cramps, bloating, increased flatus, [[nausea]], and fatigue
*can last days to over a month
*can last days to over a month
*In immunocompromised hosts, cyclospora may cause severe, intractable, voluminous diarrhea resembling cryptosporidiosis. Extraintestinal disease in patients with AIDS may include cholecystitis and disseminated infection.
*In immunocompromised hosts, cyclospora may cause severe, intractable, voluminous diarrhea resembling cryptosporidiosis. Extraintestinal disease in patients with [[AIDS]] may include cholecystitis and disseminated infection.


==Diagnosis==
==Diagnosis==

Revision as of 23:23, 14 July 2016

Background

  • one celled microscopic parasite that causes intestinal infection
  • fecal-oral transmission
  • endemic in tropical and subtropical regions

Signs/Symptoms

  • watery (sometimes explosive) diarrhea, loss of appetite, weight loss, [[abdominal pain/cramps, bloating, increased flatus, nausea, and fatigue
  • can last days to over a month
  • In immunocompromised hosts, cyclospora may cause severe, intractable, voluminous diarrhea resembling cryptosporidiosis. Extraintestinal disease in patients with AIDS may include cholecystitis and disseminated infection.

Diagnosis

  • stool O&P
  • Detection is facilitated by staining stool samples with modified acid-fast stain or modified safranin stain. Multiple (≥ 3) stool specimens may be needed because cyst secretion may be intermittent (2)

Management

  • Bactrim: 160 mg TMP and 800 mg SMX po bid for 7 to 10 days for cyclosporiasis or for 10 days. Children are given 5 mg/kg TMP and 25 mg/kg SMX po bid for the same number of days.
  • Immunocompromised patients may require higher doses and longer duration of treatment, and treatment of acute infection is usually followed by long-term suppressive therapy

References