Acrylonitrile toxicity: Difference between revisions

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=Background=
==Background==
*Unique type of Cyanide toxicity
*Unique type of [[Cyanide|Cyanide toxicity]]
*Used in the production of plastics
*Used in the production of plastics
**'''Structure:''' Nitrile group linked to a Vinyl group
**'''Structure:''' Nitrile group linked to a Vinyl group


=Mechanism of Action=
===Mechanism of Action===
*Chemical itself is hepatotoxic
*Chemical itself is hepatotoxic
*Also metabolized to form cyanide molecule
*Also metabolized to form cyanide molecule


=Treatment=
==Clinical Features==
 
==Differential Diagnosis==
 
==Evaluation==
 
==Management==
*[[Cyanide#Treatment|Cyanide Antidotes]]
*[[Cyanide#Treatment|Cyanide Antidotes]]
*[[N-Acetylcysteine|N-Acetylcysteine]]
*[[N-Acetylcysteine|N-Acetylcysteine]]


===Sources===
==References==
*Haddad and Wincester's Toxicology page 1309
<references/>
*[[Wikipedia:Acrylonitrile|Wikipedia]]


[[Category:Tox]]
[[Category:Toxicology]]

Latest revision as of 21:56, 21 July 2016

Background

  • Unique type of Cyanide toxicity
  • Used in the production of plastics
    • Structure: Nitrile group linked to a Vinyl group

Mechanism of Action

  • Chemical itself is hepatotoxic
  • Also metabolized to form cyanide molecule

Clinical Features

Differential Diagnosis

Evaluation

Management

References