Mediastinitis: Difference between revisions

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==Background==
==Background==
* A serious infection of the mediastinum with significant morbidity and mortality and generally requires surgery
*Inflammation of the mediastinum
**Commonly caused by esophageal rupture or perforation
**Infection may be caused by esophageal rupture/perforation or spread of infection from remote site
***Streptococcus and Bacteroides
 
===Etiology===
*Prior cardiovascular surgery (most common cause)<ref>Infections of the mediastinum. SB  - Thorac Surg Clin 2009 Feb; PMID 19288819 </ref>
*[[Esophageal Perforation|Esophageal rupture (Boerhaave Syndrome)]]
*[[Ludwig Angina]]
*[[Thoracic Trauma]]
*Lung infection extension


==Clinical Features==
==Clinical Features==
* Chest Pain
*[[Fever]]
* Signs of [[Sepsis]]
*[[Dyspnea]]
* Hamman sign on auscultation of precordium (crunch heard during systole)
*[[Chest pain]]
*[[Neck pain]] and swelling
**Crepitus
*Signs of [[Sepsis]]
*Hamman sign on auscultation of precordium (crunch heard during systole)


==Etiology==
==Differential Diagnosis==
* Prior cardiovascular surgery (most common cause)
* [[Esophageal perforation|Esophageal rupture (Boerhaave Syndrome)]]
* [[Ludwig Angina]]
* Trauma
* Lung infection extension


==Workup==
==Evaluation==
* Septic workup to include:
*[[CXR]] - often first modality
** CBC
**Typically reveals subcutaneous emphysema, widening of the mediastinum and pleural effusions
** Blood cultures
*CT with IV contrast if diagnosis in doubt
** Gram Stain
*Septic workup to include:
** Cultures of mediastinal pacing wires
**CBC
* CT if diagnosis in doubt
**Lactic acid
**Blood cultures (incl gram Stain)
**Cultures of mediastinal fluid


==Management==
==Management==
* ''Patients with mediastinitis require surgery''
*Aggressive airway management
* Start broad-spectrum antibiotics to include Pseudomonal coverage
*''Patients with mediastinitis emergently require surgery''
**Consult
***CT Surgery for repair
***ENT if upper neck area
***GI for possible endoscopy
*Start broad-spectrum antibiotics to include Pseudomonal coverage<ref>El Oakley, RM et al. Postoperative mediastinitis: classification and management. Ann Thorac Surg. 1996. PMID 8619682</ref>
 
==Disposition==
==Disposition==
* Admit
*Admit to ICU
 
==See Also==
==See Also==
*[[Pneumomediastinum]]
*[[Thoracic Trauma]]


==Sources==
==References==
<references/>
<references/>
[[Category:ID]]
[[Category:Pulmonary]]

Latest revision as of 16:16, 9 September 2016

Background

  • Inflammation of the mediastinum
    • Commonly caused by esophageal rupture or perforation
    • Infection may be caused by esophageal rupture/perforation or spread of infection from remote site
      • Streptococcus and Bacteroides

Etiology

Clinical Features

Differential Diagnosis

Evaluation

  • CXR - often first modality
    • Typically reveals subcutaneous emphysema, widening of the mediastinum and pleural effusions
  • CT with IV contrast if diagnosis in doubt
  • Septic workup to include:
    • CBC
    • Lactic acid
    • Blood cultures (incl gram Stain)
    • Cultures of mediastinal fluid

Management

  • Aggressive airway management
  • Patients with mediastinitis emergently require surgery
    • Consult
      • CT Surgery for repair
      • ENT if upper neck area
      • GI for possible endoscopy
  • Start broad-spectrum antibiotics to include Pseudomonal coverage[2]

Disposition

  • Admit to ICU

See Also

References

  1. Infections of the mediastinum. SB - Thorac Surg Clin 2009 Feb; PMID 19288819
  2. El Oakley, RM et al. Postoperative mediastinitis: classification and management. Ann Thorac Surg. 1996. PMID 8619682