Docusate: Difference between revisions
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<languages/> | |||
<translate> | |||
==Administration== | ==Administration== | ||
*Type: stool softener; [[laxitive]] | |||
*Type: stool softener; [[Special:MyLanguage/laxitive|laxitive]] | |||
*Dosage Forms: | *Dosage Forms: | ||
*Routes of Administration: Oral, rectal | *Routes of Administration: Oral, rectal | ||
*Common Trade Names: Colace | *Common Trade Names: Colace | ||
==Adult Dosing== | ==Adult Dosing== | ||
*50 to 200mg daily or in 2-4 divided doses | *50 to 200mg daily or in 2-4 divided doses | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*<3y: 10 to 40mg/day in 1-4 divided doses | *<3y: 10 to 40mg/day in 1-4 divided doses | ||
*3-6y: 20 to 60mg/day in 1-4 divided doses | *3-6y: 20 to 60mg/day in 1-4 divided doses | ||
*6-12y: 40 to 120mg/day in 1-4 divided doses | *6-12y: 40 to 120mg/day in 1-4 divided doses | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: A | |||
*[[Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out | *[[Special:MyLanguage/Drug Ratings in Pregnancy|Pregnancy Rating]]: A | ||
*[[Special:MyLanguage/Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out | |||
===Renal Dosing=== | ===Renal Dosing=== | ||
*Adult: | *Adult: | ||
*Pediatric: | *Pediatric: | ||
===Hepatic Dosing=== | ===Hepatic Dosing=== | ||
*Adult: | *Adult: | ||
*Pediatric: | *Pediatric: | ||
==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
*Acute obstruction | *Acute obstruction | ||
*Acute abdominal pain, vomiting | *Acute abdominal pain, vomiting | ||
*concurrent use of mineral oil | *concurrent use of mineral oil | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Hepatotoxicity (Rare) | *Hepatotoxicity (Rare) | ||
===Common=== | ===Common=== | ||
*[[Diarrhea]], nausea, cramping | |||
*[[Special:MyLanguage/Diarrhea|Diarrhea]], nausea, cramping | |||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: | ||
*Metabolism: | *Metabolism: | ||
*Excretion: | *Excretion: | ||
==Mechanism of Action== | ==Mechanism of Action== | ||
*Draws water into stool | *Draws water into stool | ||
==Comments== | ==Comments== | ||
==See Also== | ==See Also== | ||
*[[Constipation]] | |||
*[[Lactulose]] | *[[Special:MyLanguage/Constipation|Constipation]] | ||
*[[Special:MyLanguage/Lactulose|Lactulose]] | |||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:GI]] | [[Category:GI]] | ||
</translate> | |||
Latest revision as of 22:49, 4 January 2026
Administration
- Type: stool softener; laxitive
- Dosage Forms:
- Routes of Administration: Oral, rectal
- Common Trade Names: Colace
Adult Dosing
- 50 to 200mg daily or in 2-4 divided doses
Pediatric Dosing
- <3y: 10 to 40mg/day in 1-4 divided doses
- 3-6y: 20 to 60mg/day in 1-4 divided doses
- 6-12y: 40 to 120mg/day in 1-4 divided doses
Special Populations
- Pregnancy Rating: A
- Lactation risk: Infant risk cannot be ruled out
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
- Acute obstruction
- Acute abdominal pain, vomiting
- concurrent use of mineral oil
Adverse Reactions
Serious
- Hepatotoxicity (Rare)
Common
- Diarrhea, nausea, cramping
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Draws water into stool