Tetrahydrozyline: Difference between revisions
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==Administration== | ==Administration== | ||
*Type: Adrenergic agonist, decongestant, vasoconstrictor; imidazoline derivative | *Type: Adrenergic agonist, [[decongestant]], vasoconstrictor; imidazoline derivative<ref>Tetrahydrozoline (nasal): Drug information. Uptodate. www.uptodate.com. Accessed July 30th, 2020.</ref><ref>Tetrahydrozoline (opthalmic): Drug information. Uptodate. www.uptodate.com. Accessed July 30th, 2020.</ref> | ||
*Dosage Forms: 0.05% solution, 0.1% solution | *Dosage Forms: 0.05% solution, 0.1% solution | ||
*Routes of Administration: Nasal, ophthalmic | *Routes of Administration: Nasal, ophthalmic | ||
*Common Trade Names: Tyzine | *Common Trade Names: Tyzine Eye Drops, GoodSense Eye Drops, GoodSense Relief Eye Drops, Opti-Clear, Visine Advanced Relief | ||
==Adult Dosing== | ==Adult Dosing== | ||
| Line 39: | Line 39: | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Coma, bradycardia, respiratory depression, sedation in children with even small (1-1ml) ingestions | *[[Coma]], [[bradycardia]], respiratory depression, sedation in children with even small (1-1ml) ingestions | ||
===Common=== | ===Common=== | ||
| Line 64: | Line 64: | ||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
Latest revision as of 18:49, 8 February 2022
Administration
- Type: Adrenergic agonist, decongestant, vasoconstrictor; imidazoline derivative[1][2]
- Dosage Forms: 0.05% solution, 0.1% solution
- Routes of Administration: Nasal, ophthalmic
- Common Trade Names: Tyzine Eye Drops, GoodSense Eye Drops, GoodSense Relief Eye Drops, Opti-Clear, Visine Advanced Relief
Adult Dosing
- Nasal congestion
- 2-4 drops or 3-4 sprays 0.1% solution into each nostril every 3-4 hours as needed
- Ocular decongestant
- 1-2 drops in affected eye up to 4 times a daily
Pediatric Dosing
- Nasal congestion:
- Children 2-6 years: 2-3 drops 0.05% solution into each nostril every 406 hours as needed
- Children >6 years: adult dosing
- Ocular decongestant:
- Children >6 years: adult dosing
Special Populations
Pregnancy Rating
- C
Lactation risk
- Unknown
Renal Dosing
- Adult: N/A
- Pediatric: N/A
Hepatic Dosing
- Adult: N/A
- Pediatric: N/A
Contraindications
- Allergy to class/drug
- 0.5% solution is contraindicated in children <2; 0.1% solution is contraindicated in children <6
Adverse Reactions
Serious
- Coma, bradycardia, respiratory depression, sedation in children with even small (1-1ml) ingestions
Common
- Sneezing, stinging sensation in nose
- Hypertension, palpitations, tachycardia
- Headache
- Tremor
- Blurred vision
Pharmacology
- Half-life: N/A
- Metabolism: N/A
- Excretion: N/A
Mechanism of Action
- Alpha adrenergic agonist - arteriolar constriction