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| ==Background==
| | #REDIRECT[[Reactive arthritis]] |
| *Seronegative spondyloarthropathy that manifests as an acute, asymmetric, oligoarthritis (LE>UE) that occurs 2-6 weeks after infection
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| *Classic triad: urethritis, conjunctivitis, and arthritis ("Can't pee, can't see, can't climb a tree")
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| ==Clinical Features==
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| *Preceding Infection
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| **Urethritis: generally caused by Chlamydia or Ureaplasma
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| **Enteritis: generally caused by Salmonella or Shigella
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| **Preceding infection may be clinically silent
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| *Musculoskeletal symptoms
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| **Arthritis: oligoarthritis, usually in the lower extremities
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| **Enthesitis (pain at insertion sites)
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| **Dactylitis (sausage digits)
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| **Low back pain
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| *Extraarticular symptoms
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| **Conjunctivitis (less frequently uveitis, keratitis)
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| **GU symptoms
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| **Oral lesions
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| **Cutaneous and nail changes
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| ==Differential Diagnosis==
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| *Gonococcal Arthritis
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| *Rheumatoid Arthritis
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| *Psoriatic Arthritis
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| *Ankylosing Spondylitis
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| *Lupus
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| ==Diagnosis==
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| *Primarily a clinical diagnosis, no definitive test
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| *More likely if there is the presence of:
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| **Characteristic musculoskeletal findings
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| **Presence of preceding illness
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| **Lack of more likely cause of arthritis
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| ==Management==
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| *Treat inciting infection
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| *Symptomatic treatment of arthritis
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| **NSAIDs are first line (naproxen, diclofenac, indomethacin)
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| **Intraarticular and systemic steroids for NSAID refractory
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| ==Disposition==
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| *Referral to a rheumatologist
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| ==References==
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| <references/>
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