Antihistamines: Difference between revisions

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==Types==
==Types==
===H1 antagonist===
===H<sub>1</sub> antagonists===
*[[Brompheniramine]] (Dimetane)
*[[Brompheniramine]] (Dimetane)
*[[Cetirizine]] (Zyrtec)
*[[Cetirizine]] (Zyrtec)
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*[[Hydroxyzine]] (Vistaril)
*[[Hydroxyzine]] (Vistaril)
*[[Loratadine]] (Claritin)
*[[Loratadine]] (Claritin)
*[[Meclozine]]
*[[Meclizine]]


===H<sub>2</sub>-receptor antagonists===
===H<sub>2</sub> antagonists===
*[[Cimetidine]]
*[[Cimetidine]]
*[[Famotidine]]
*[[Famotidine]]
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**[[Insomnia]]
**[[Insomnia]]
**[[Vertigo]]
**[[Vertigo]]
**[[Motion sickness]]
**[[Nausea and vomiting in pregnancy]]
*H<sub>2</sub> antagonists
*H<sub>2</sub> antagonists
**[[GERD]]/[[peptic ulcers]]
**[[GERD]]/[[peptic ulcers]]
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*Sedation
*Sedation
**Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness
**Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness
*[[Anticholinergic toxicity]]


==See Also==
==See Also==

Latest revision as of 22:33, 7 March 2021

Background

  • Also known as histamine antagonists
  • In common use, the term antihistamine refers only to compounds that inhibit action at the H1 receptor (and not H2, etc.).

Types

H1 antagonists

H2 antagonists

Indications

Side Effects

  • Sedation
    • Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness

See Also

References