Synthetic cannabinoids: Difference between revisions
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==Clinical Features= | ==Clinical Features= | ||
*Similar effect to marijuana at low doses, but may be more intense and cause an acute | *Similar effect to marijuana at low doses, but may be more intense and cause an acute '''agitated delerium''' | ||
*Typical effects 10-30 min and taper over 1-2 hours | *Typical effects 10-30 min and taper over 1-2 hours | ||
* | *'''Tachycardia and hypertension''' common (distinguishing it from MJ use) | ||
*Adverse effects: nausea, vomiting, diaphoresis, anxiety, paranoia, hallucinations, agitation, deli | *Adverse effects: nausea, vomiting, diaphoresis, anxiety, paranoia, hallucinations, agitation, deli | ||
==Treatment== | ==Treatment== | ||
*Supportive | *Supportive | ||
*Benzodiazepines | *Benzodiazepines | ||
*Zofran | *Zofran | ||
Revision as of 15:19, 25 September 2012
Background
- Common names: spice, K2, Moon Rocks, Blue Lotus, many others
- Active ingredients: cannabicyclohexano, JWH-018, JWH-073, HU-210, others
- Far more potent than THC (100-800x)
- Cannabinoid receptor agonists (CB1 or CB2)
- Do not show up as marijuana on routine tox testing
- Generally smoked, but can be drank as a tea
=Clinical Features
- Similar effect to marijuana at low doses, but may be more intense and cause an acute agitated delerium
- Typical effects 10-30 min and taper over 1-2 hours
- Tachycardia and hypertension common (distinguishing it from MJ use)
- Adverse effects: nausea, vomiting, diaphoresis, anxiety, paranoia, hallucinations, agitation, deli
Treatment
- Supportive
- Benzodiazepines
- Zofran
Source
David Burbulys, MD lecture 9/2012