Mesenteric panniculitis: Difference between revisions
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==Background== | ==Background== | ||
*Also known as sclerosing mesenteritis, mesenteric lipodystrophy, mesenteric sclerosis, retractile mesenteritis, mesenteric Weber-Christian disease, liposclerotic mesenteritis, lipomatosis and lipogranuloma of the mesentery<ref name="Issa">Issa I and Baydoun H. Mesenteric panniculitis: Various presentations and treatment regimens. World J Gastroenterol. 2009 Aug 14; 15(30): 3827–3830.</ref> | *Also known as sclerosing mesenteritis, mesenteric lipodystrophy, mesenteric sclerosis, retractile mesenteritis, mesenteric Weber-Christian disease, liposclerotic mesenteritis, lipomatosis and lipogranuloma of the mesentery<ref name="Issa">Issa I and Baydoun H. Mesenteric panniculitis: Various presentations and treatment regimens. World J Gastroenterol. 2009 Aug 14; 15(30): 3827–3830.</ref> | ||
*A rare, benign, and chronic fibrosing inflammatory disease that affects the adipose tissue of the mesentery (of the small intestine and colon)<ref name="Issa" />. | *A rare, benign, and chronic fibrosing inflammatory disease that affects the adipose tissue of the mesentery (of the small intestine and colon)<ref name="Issa" />. | ||
*Occurs independently (specific cause unknown) or in association with other disorders<ref name="Issa" /> | *Occurs independently (specific cause unknown) or in association with other disorders<ref name="Issa" /> | ||
==Clinical Features== | ==Clinical Features== | ||
*[[Abdominal pain]] | |||
*[[Special:MyLanguage/Abdominal pain|Abdominal pain]] | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
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==Evaluation== | ==Evaluation== | ||
*Regional increase in mesenteric fat density on abdominal CT (i.e. “misty mesentery”) | *Regional increase in mesenteric fat density on abdominal CT (i.e. “misty mesentery”) | ||
**May be confirmed by surgical biopsy | **May be confirmed by surgical biopsy | ||
==Management== | ==Management== | ||
*Supportive ED treatment | *Supportive ED treatment | ||
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*Chronic treatment includes workup of underlying etiology and consideration of medical therapy for severe/protracted disease (e.g. corticosteroids, cyclophosphamide, or azathioprine) | *Chronic treatment includes workup of underlying etiology and consideration of medical therapy for severe/protracted disease (e.g. corticosteroids, cyclophosphamide, or azathioprine) | ||
==Disposition== | ==Disposition== | ||
*Outpatient | *Outpatient | ||
==Prognosis== | ==Prognosis== | ||
*Overall prognosis is usually good and recurrence seems to be rare<ref name="Issa" /> | *Overall prognosis is usually good and recurrence seems to be rare<ref name="Issa" /> | ||
==See Also== | ==See Also== | ||
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==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:GI]] | [[Category:GI]] | ||
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Revision as of 23:45, 4 January 2026
Background
- Also known as sclerosing mesenteritis, mesenteric lipodystrophy, mesenteric sclerosis, retractile mesenteritis, mesenteric Weber-Christian disease, liposclerotic mesenteritis, lipomatosis and lipogranuloma of the mesentery[1]
- A rare, benign, and chronic fibrosing inflammatory disease that affects the adipose tissue of the mesentery (of the small intestine and colon)[1].
- Occurs independently (specific cause unknown) or in association with other disorders[1]
Clinical Features
Differential Diagnosis
Evaluation
- Regional increase in mesenteric fat density on abdominal CT (i.e. “misty mesentery”)
- May be confirmed by surgical biopsy
Management
- Supportive ED treatment
There is no standardized treatment, and it may consist of anti-inflammatory or immunosuppressive agents. We recommend resection only when the advanced inflammatory changes become irreversible or in cases of bowel obstruction
- Chronic treatment includes workup of underlying etiology and consideration of medical therapy for severe/protracted disease (e.g. corticosteroids, cyclophosphamide, or azathioprine)
Disposition
- Outpatient
Prognosis
- Overall prognosis is usually good and recurrence seems to be rare[1]