Drug induced aseptic meningitis: Difference between revisions
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*IVIGs | *IVIGs | ||
*OKT3 monoclonal antibodies | *OKT3 monoclonal antibodies | ||
==Clinical presentation== | |||
*[[Headache]] | |||
*[[Fever]] | |||
*Nuchal rigidity | |||
*[[Nausea/vomiting]] | |||
*General malaise | |||
*Less common symptoms include rash, arthralgia, myalgia, facial edema | |||
Revision as of 17:42, 1 September 2017
Background
- Abbreviation: DIAM
- Two proposed mechanisms
- Direct meningeal irritation by intrathecal drug
- Hypersensitivity reaction to drug (type III and IV)
Causes
- NSAIDs
- Antibiotics
- IVIGs
- OKT3 monoclonal antibodies
Clinical presentation
- Headache
- Fever
- Nuchal rigidity
- Nausea/vomiting
- General malaise
- Less common symptoms include rash, arthralgia, myalgia, facial edema