Diazepam: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
* Anxiety | |||
** PO: 2 - 10 mg 2-4 times daily | |||
* Muscle spasm | |||
** PO: 2 - 10 mg 2-4 times daily | |||
* Sedation in ICU | |||
** IV: Loading dose: 5 - 10 mg, Maintenance dose: 0.03 - 0.1 mg/kg every 30 minutes to 6 hours | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 18:58, 2 April 2019
General
- Type: Benzodiazepines
- Dosage Forms:
- Common Trade Names: Valium
Adult Dosing
- Anxiety
- PO: 2 - 10 mg 2-4 times daily
- Muscle spasm
- PO: 2 - 10 mg 2-4 times daily
- Sedation in ICU
- IV: Loading dose: 5 - 10 mg, Maintenance dose: 0.03 - 0.1 mg/kg every 30 minutes to 6 hours
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
- severe hepatic impairment
Adverse Reactions
Serious
- Respiratory/CNS depression
- Hypotension
- paradoxical CNS stimulation
Common
- drowsiness
- disinhibition
- ataxia
Pharmacology
- Half-life: 30-60 hours
- Metabolism: Liver
- Excretion: Urine
- Mechanism of Action: GABA agonist