Fresh frozen plasma: Difference between revisions
(Created page with "==Features== #Contains all coagulation factors and fibrinogen ##40 mL/kg raises any factor by 100% (each unit is ~200mL) #May cause fluid overload #ABO compatibilty a must but...") |
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#ABO compatibilty a must but crossmatch before transfusing not | #ABO compatibilty a must but crossmatch before transfusing not | ||
#INR of FFP is ~1.2 | #INR of FFP is ~1.2 | ||
#Retains active coagulation factors for up to 5 days after being thawed | |||
==Indications== | ==Indications== | ||
Revision as of 03:02, 5 February 2015
Features
- Contains all coagulation factors and fibrinogen
- 40 mL/kg raises any factor by 100% (each unit is ~200mL)
- May cause fluid overload
- ABO compatibilty a must but crossmatch before transfusing not
- INR of FFP is ~1.2
- Retains active coagulation factors for up to 5 days after being thawed
Indications
- Rapid reversal of warfarin over-anticoagulation
- Bleeding and multiple coagulation defects
- Correction of coagulation defects for which no specific factor is available
- Transfusion of more than one blood volume w/ evidence of active bleeding + coagulopathy
Dose
- Transfuse at least 15 mL/kg at a time (4 units in 70-kg adult)
See Also
Source
Tintinalli