Anion gap: Difference between revisions
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==Source== | ==Source== | ||
Kaji Questions | Kaji Questions <br /> | ||
MISTRY 6/06 | MISTRY 6/06 | ||
[[Category:FEN]] | [[Category:FEN]] | ||
[[Category:Tox]] | [[Category:Tox]] | ||
Revision as of 16:04, 7 February 2014
Elevated Anion Gap
DDx
MUDPILES
- M - Methanol
- U - Uremia
- D - DKA
- P - Paraldehyde
- I - Iron, INH
- L - Lactic acidosis
- E - Ethylene glycol
- S - Salicylates
Also:
- Starvation/ETOH ketoacidosis
- CO, CN poisoning (incr. lactate)
Low Anion Gap
Background
- < 7 meq/L
DDX
- Lab error
- Decreased "unmeasured" anions
- hypoalbuminemia
- Increased "unmeasured" cations
- Increased cationic paraprotein
- Multiple myeloma
- Polyclonal IgG gammopathy
- Pseudo
- Severe Hypernatremia (>170 meq/L)
- True conc of Na is underestimated
- Marked hyperlipidemia
- Leads to overestimation of plasma Cl conc)
- Bromide intoxication (e.g. for myasthenia gravis and some herbal medications)
- Machine mistakenly reads Br as Cl
- Severe Hypernatremia (>170 meq/L)
- AG falls by 2.5 meq/L for every 1 g/dL reduction in albumin concentration
See Also
Anion Gap and Osmolar Gap (High)
Source
Kaji Questions
MISTRY 6/06