Systemic lupus erythematosus: Difference between revisions
m (Rossdonaldson1 moved page Systemic lupus erythematosus to Systemic Lupus Erythematosus) |
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==Background== | ==Background== | ||
*Autoimmune disorder | *Autoimmune disorder affecting all sysems | ||
==Epidemiology== | ==Epidemiology== | ||
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'''Flairs''' | '''Flairs''' | ||
*Cardiopulmonary | |||
**Pneumonia | |||
***Cover for ''[[Listeria]]'' and ''[[Pseudmonas]]'' | |||
**CAD | |||
**[[PE]] | |||
**[[Pericarditis]] | |||
**[[Endocarditis]] | |||
***Infectious and Libman-Sachs | |||
*Neuropsychartic/Altered mental status | |||
**Non-convulsive status epilepticus | |||
**CNS vasculitis | |||
**[[Stroke]] | |||
**[[Encephalitis]] | |||
*Musculoskeletal | |||
Revision as of 22:23, 25 March 2014
Background
- Autoimmune disorder affecting all sysems
Epidemiology
- Femaile:Male 10:1
- More common in African Americans
Clinical Features
Diagnostic Criteria: 4 out of 11 of the following:
- Malar rash
- Discoid rash
- Photosensitivity
- Oral ulcers
- Arthritis (polyarticular)
- Serositis (Pericarditis or pleuritis)
- Renal disorder (renal failure, protenuria, casts)
- Neurologic or psychotic symptoms
- Hematologic (anemia, thrombocytopenia, or leukopenia)
- Immunologic (+antibofy testing)
- ANA (positive ANA)
New Presentations
Flairs
- Cardiopulmonary
- Pneumonia
- Cover for Listeria and Pseudmonas
- CAD
- PE
- Pericarditis
- Endocarditis
- Infectious and Libman-Sachs
- Pneumonia
- Neuropsychartic/Altered mental status
- Non-convulsive status epilepticus
- CNS vasculitis
- Stroke
- Encephalitis
- Musculoskeletal
Differential Diagnosis
- Rheumatoid arthritis
- Sjogren's syndrome
- Dermatomyositis
- Polymyositis
- Stevens-Johnson syndrome
- Toxic Epidermal Necrolysis
- Septic arthritis
- Lyme disease
- Vasculitis
- Acute Rheumatic Fever
- Toxic Shock Syndrome
- TTP
- ITP
- DIC
Workup
Undiagnosed
- CBC
- Chem 10
- ANA
- ESR
- UA
- Bedside echo if ill or hypotensive
Flair
- Bedside echo if ill or hypotensive
- CBC
Management
- Steroids
Disposition
See Also
Arthritis Fever and Rash Lupus Anticoagulant Pericarditis Pericardial Effusion and Tamponade Acute Renal Failure Adrenal Crisis
Sources
- Rosen's
- Up to date