Rocuronium

General

• Type: Neuromuscular blocker, Non-Depolarizing, Fast Onset, Intermediate Lasting
• Dosage Forms: IV
• Common Trade Names: Zemuron

Adult Dosing

RSI is 0.6 to 1.2 mg/kg IV (actual body weight)

Pediatric Dosing

RSI is 0.6 to 1.2 mg/kg IV (actual body weight)

Special Populations

• Pregnancy Rating: C
• Lactation: Infant risk cannot be ruled out
• Renal Dosing (half life approximately 1 hour longer if renal transplant patient)
  • Adult
  • Pediatric
• Hepatic Dosing (half life approximately 3 hours longer with liver dysfunction)
  • Adult
  • Pediatric

Contraindications

• Allergy to class/drug

Adverse Reactions

Serious

Anaphylaxis

Common

Cardiovascular: HTN (0.1% to 2%). Hypotension (0.1% to 2%). Tachycardia (1% to 5.3%) Dermatologic: Pain at injection site Respiratory: Increased pulmonary vascular resistance (24%)

Pharmacology

• Half-life:
• Metabolism:
• Excretion:
• Mechanism of Action: