Hydrogen sulfide toxicity: Difference between revisions
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==Background== | |||
#Colorless, flammable gas w/ rotten egg odor | |||
#Encountered in oil/gas industries, natural product of decomposition (e.g. septic tank) | |||
#Mechanism of toxicity is similar to CN (disruption of aerobic metabolism) | |||
==Clinical Features== | |||
#One of the few chemical asphyxiants that also possesses irritative properities | |||
##Respiratory, ocular irritation | |||
#High conc exposure may result in LOC, sz, and death after only a few breaths | |||
##Delayed pulm edema and corneal destruction should be anticipated w/ massive exposures | |||
==Treatment== | |||
#Decontamination of skin/eyes | |||
#O2 100% NRB | |||
#Consider giving nitrite component of CN kit (do not give thiosulfate portion) | |||
##Low level MetHb may enhance conversion of sulfide to less toxic sulfmethemoglobin | |||
==Source== | |||
Tintinalli | |||
[[Category:Tox]] | [[Category:Tox]] | ||
Revision as of 06:09, 22 September 2011
Background
- Colorless, flammable gas w/ rotten egg odor
- Encountered in oil/gas industries, natural product of decomposition (e.g. septic tank)
- Mechanism of toxicity is similar to CN (disruption of aerobic metabolism)
Clinical Features
- One of the few chemical asphyxiants that also possesses irritative properities
- Respiratory, ocular irritation
- High conc exposure may result in LOC, sz, and death after only a few breaths
- Delayed pulm edema and corneal destruction should be anticipated w/ massive exposures
Treatment
- Decontamination of skin/eyes
- O2 100% NRB
- Consider giving nitrite component of CN kit (do not give thiosulfate portion)
- Low level MetHb may enhance conversion of sulfide to less toxic sulfmethemoglobin
Source
Tintinalli
