Pacemaker complication: Difference between revisions

Line 125: Line 125:
**Break with [[adenosine]] or magnet.<ref>EB Medicine- Sept 2014- Managing Pacemaker-Related Complications and Malfunctions in the Emergency Department </ref>
**Break with [[adenosine]] or magnet.<ref>EB Medicine- Sept 2014- Managing Pacemaker-Related Complications and Malfunctions in the Emergency Department </ref>
**Consider chest wall stimulation techniques<ref>Barold SS, Falkoff MD, Ong LS, Heinle RA. Pacemaker endless loop tachycardia: termination by simple techniques other than magnet application. Am J Med. 1988;85(6):817-22.</ref> - transcutaneous pacing, isometric muscular exercise, precordial thump
**Consider chest wall stimulation techniques<ref>Barold SS, Falkoff MD, Ong LS, Heinle RA. Pacemaker endless loop tachycardia: termination by simple techniques other than magnet application. Am J Med. 1988;85(6):817-22.</ref> - transcutaneous pacing, isometric muscular exercise, precordial thump
*Use magnet to convert pacemaker to asynchronous mode if oversensing or runaway pacing
*Electrophysiology or cardiology consult is often needed
*Contact a device representative for a full interrogation


==Disposition==
==Disposition==

Revision as of 21:22, 2 March 2021

Background

Nomenclature

Paced rhythm with characteristic wide LBBB and pacer spikes
PA Xray with pacemaker
Atrial Sensed Ventricular Paced ECG
Pacer type based on Xray
I II III IV V
Generic code for antibradycardia pacing[1]
Chamber(s) paced Chamber(s) sensed Response to sensing Rate modulation Multisite pacing
O = None O = None O = None O = None O = None
A = Atrium A = Atrium T = Triggered R = Rate modulation A = Atrium
V = Ventricle V = Ventricle I = Inhibited V = Ventricle
D = Dual (A+V) D = Dual (A+V) D = Dual (T+I) D = Dual (A+V)

Indications

  • Sinus Node Dysfunction-sinus bradycardia/arrest, sinoatrial block, chronotropic incompetence, a-fib.
  • Acquired AV block- 3rd degree block and 2nd degree type II
  • Chronic Bifascicular or Trifascicular block
  • After Acute MI-high mortality with persistent AV block post MI
  • Cardiac Resynchronization Therapy- Conduction delay (>150msec with mortality benefit) in chronic systolic heart failure further decreases EF, increases remodeling and increased MR.
  • Neurocardiogenic Syncope and Carotid Sinus Syndrome

Methods to Identify Manufacturer

  • Patient most often has a pocket card indicating manufacturer
  • Manufacturer Hotline has patient database
    • Medtronic Inc. (1-800-328-2518)
    • St. Jude Medical Inc. (recently acquired by Abbott, Inc.) (1-800-722-3774)
    • Boston Scientific Inc. (1-800-227-3422)
  • Magnet mode - with placement of a magnet over the device, the mode changes to asynchronous (i.e. DOO or VOO). Each brand has slightly different rates
    • Medtronic Inc.: 85 bpm; 65 bpm when battery is ready for replacement
    • St. Jude Medical Inc.: 98.6 bpm; 86.3 bpm when battery is ready for replacement
    • Boston Scientific Inc.: 100 bpm; 85 bpm when battery is ready for replacement
  • Manufacturer code on pulse generator is visible on Chest Xray

Electromagnetic Interference

  • Nonmedical
    • Cell phones: do not interact with device
    • Airport security: may trigger alarm, no alteration of activity
  • Medical Sources
    • MRI: mostly safe, consult cards on device specific recs
    • Cardioversion: Use AP pads >8cm from device to minimize adverse effects
    • Unipolar Cautery - can cause sensing and pacing malfunction as well as reprogramming

Differential Diagnosis

Pacemaker Malfunction

Problems with pocket

  • Infection
    • Most commonly S. aureus or S. epidermidis
    • 2% local wound infection; 1% sepsis/bacteremia
  • Hematoma
    • Typically occurs shortly after placement

Problems with leads

  • Dislodgment
  • Perforation (most commonly at RV apex)
  • Infection can cause severe sepsis
  • Tricuspid regurgitation
  • Coiling (ie: Twiddler's Syndrome)
    Twiddler Syndrome after large pocket and pacemaker wires spinning on themselves

Failure to Capture

  • Delivery of pacing stimulus without depolarization
    • Functional - refractory myocardium, desensitized local tissue around the lead
    • Medical - drugs, myocardial disease, electrolytes
    • Technical - insufficient device output, lead dislodgment, fracture, insulation defect, ventricular wall perforation

Failure to Pace

  • Failure to deliver a stimulus to the heart
    • Oversensing - most common cause: retrograde P’s, T’s, skeletal muscle myopotentials,
    • Crosstalk - type of oversensing where the ventricular lead senses atrial pacing stimulus, and ventilator output inhibited

Failure to Sense

  • Normal function: a sensed myocardial depolarization greater than the programmed threshold causes inhibition of pacing
  • Failure to sense results in a paced beat on top of an intrinsic beat (as the device is "unaware" of the intrinsic beat")
    • Voltages of patient's intrinsic QRS complex is too low to be detected
    • New intrinsic arrhythmia (AF has a smaller depolarization than sinus beat), AMI, electrolyte abnormalities, lead separation, battery depletion

Runaway Pacing

  • Physiologic electrical activity (T waves, muscle potentials)
  • External electromagnetic interference
  • Signals generated by interaction of different portions of the pacing system
  • Potentially life-threatening as it can cause V-Fib or (paradoxically) bradycardia due to failure to capture

Pacemaker Mediated Tachycardia

  • Also known as Endless Loop Tachycardia
  • Formation of a re-entrant circuit causing inappropriate tachycardia
    • Most commonly: paced ventricular beat -> retrograde AV node conduction -> intrinsic P wave -> device reacts to intrinsic P wave by looking for intrinsic QRS, but since AV node is now refractory it delivers a paced beat at the programmed P-R interval (typically ~200-250ms), starting the process anew
  • Tachycardia does not exceed programmed upper limit rate on pacemaker

Evaluation

Work-Up

  • BMP and Mg
  • CXR
  • ECG
  • Troponin
  • Interrogation
    • Each company has on-call representatives who will come interrogate a device 24/7 (phone numbers above)
    • Most cath labs will have machines capable of interrogating each brand

Expected ECG Patterns

  • Absence of pacer artifact indicates intrinsic depolarization
    • With newer pacemakers, pacer spikes may not appear on some or all paced beats, depending on EKG machine
  • Pacing artifacts preceding depolarizations indicate successful pacing and capture
  • Leads in RV apex produce LBBB pattern with appropriate discordance
  • New RBBB pattern may indicate lead in LV
  • Simultaneous depol of ventricles produces dominant R wave in V1

Plain Film Findings

  • Obtain PA/Lateral Films to confirm pulse generator, manufacturer, lead placement/number/integrity
  • R atrial lead J shaped(tip medially on AP) entering right atrial appendage
  • RV leads point downward with tip between left spine and cardiac apex--lateral XR shows inferior and anterior
  • Coronary sinus lead- courses posteriorly on lateral XR
  • Extra leads may be appropriately abandoned and capped
  • ICD component appears as thickened shock coil

Management

  • Pacemaker Mediated Tachycardia
    • Break with adenosine or magnet.[2]
    • Consider chest wall stimulation techniques[3] - transcutaneous pacing, isometric muscular exercise, precordial thump
  • Electrophysiology or cardiology consult is often needed
  • Contact a device representative for a full interrogation

Disposition

  • Infection - admission with MRSA coverage antibiotics, consult to cardiology, with likely replacement of pacemaker after 4-6 weeks of IV antibiotics

See Also

References

  1. Bernstein AD. et al. The revised NASPE/BPEG generic code for antibradycardia, adaptive-rate, and multisite pacing. North American Society of Pacing and Electrophysiology/British Pacing and Electrophysiology Group. Pacing Clin Electrophysiol 2002 Feb; 25(2) 260-4. lmid:11916002
  2. EB Medicine- Sept 2014- Managing Pacemaker-Related Complications and Malfunctions in the Emergency Department
  3. Barold SS, Falkoff MD, Ong LS, Heinle RA. Pacemaker endless loop tachycardia: termination by simple techniques other than magnet application. Am J Med. 1988;85(6):817-22.