Opioid withdrawal: Difference between revisions

m (Rossdonaldson1 moved page Opioid Withdrawal to Opioid withdrawal)
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*Onset is 6-12hr after last heroin use, within 30hr after last methadone use
*Onset is 6-12hr after last heroin use, within 30hr after last methadone use


==Clinical Features==
==Clinical Presentation==
#Onset: within hours of cessation
#Onset: within hours of cessation
#Peak effects: 36-72hr
#Peak effects: 36-72hr
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##Abd pain
##Abd pain
##N/V/D
##N/V/D
==Workup==
*Normally a clinical diagnosis
**Consider a [[urine tox]]
==Differential Diagnosis==


==Treatment==
==Treatment==
#Clonidine
#[[Clonidine]]
##5mcg/kg PO (as long as SBP >90)
#*5mcg/kg PO (as long as SBP >90)
#Hydroxyzine
#[[Hydroxyzine]]
##50-100mg PO QID x5d
#*50-100mg PO QID x5d
#Antiemetics
#[[Antiemetics]]
#Antidiarrheals
#Antidiarrheals
#NSAIDS
#[[NSAIDS]]
#PO/IV hydration
#PO/IV hydration
==See Also==
*[[Neonatal abstinence syndrome]]


==Source==
==Source==

Revision as of 15:44, 12 March 2015

Background

  • Uncomfortable but not life-threatening
    • only life-threatening in neonates
  • Onset is 6-12hr after last heroin use, within 30hr after last methadone use

Clinical Presentation

  1. Onset: within hours of cessation
  2. Peak effects: 36-72hr
    1. Anxiety
    2. Craving
    3. Yawning
    4. Rhinorrhea
    5. Diaphoresis
  3. Onset: 12hr after cessation
  4. Peak effects: 72hr
    1. Tremor
    2. Piloerection
    3. Mydriasis
    4. Irritability
  5. Onset: 24-36hr after cessation
  6. Peak effects: 72hr
    1. Muscle spasm
    2. Abd pain
    3. N/V/D

Workup

  • Normally a clinical diagnosis

Differential Diagnosis

Treatment

  1. Clonidine
    • 5mcg/kg PO (as long as SBP >90)
  2. Hydroxyzine
    • 50-100mg PO QID x5d
  3. Antiemetics
  4. Antidiarrheals
  5. NSAIDS
  6. PO/IV hydration

See Also

Source

  • Tintinalli