Clopidogrel: Difference between revisions
| Line 27: | Line 27: | ||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: 8h | ||
*Metabolism: | *Metabolism: liver, CYP450: 1A2, 2C9, 2C19 (primary), 3A4 substrate | ||
*Excretion: | *Excretion: urine 50%, feces 46% | ||
*Mechanism of Action: | *Mechanism of Action: irreversibly binds to P2Y12 adenosine diphosphate receptors, reducing platelet activation and aggregation | ||
==See Also== | ==See Also== | ||
Revision as of 23:06, 26 June 2015
General
- Type: Antiplatelet
- Dosage Forms: 75, 300 PO
- Common Trade Names: Plavix
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: 8h
- Metabolism: liver, CYP450: 1A2, 2C9, 2C19 (primary), 3A4 substrate
- Excretion: urine 50%, feces 46%
- Mechanism of Action: irreversibly binds to P2Y12 adenosine diphosphate receptors, reducing platelet activation and aggregation