Superior vena cava syndrome: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
#Occurs in 3-8% with lung cancer and lymphoma | |||
#Symptoms due to venous hypertension in areas drained by SVC | |||
Occurs in 3-8% with lung cancer and lymphoma | #Deaths occurs from cerebral edema, airway compromise, or cardiac compromise | ||
Symptoms due to venous hypertension in areas drained by SVC | |||
Deaths occurs from cerebral edema, airway compromise, or cardiac compromise | |||
==Clinical features== | ==Clinical features== | ||
#Thoracic or neck vein distention - 65% | |||
#Shortness of breath - 50% | |||
Thoracic or neck vein distention - 65% | #Tachypnea - 40% | ||
#Upper trunk or extremity edema - 40% | |||
Shortness of breath - 50% | #Cough/dysphagia/chest pain - 20% | ||
#Peri-orbital or facial edema - ? | |||
Tachypnea - 40% | #Stroke's sign (tight shirt collar) - ? | ||
Upper trunk or extremity edema - 40% | |||
Cough/dysphagia/chest pain - 20% | |||
Peri-orbital or facial edema - ? | |||
Stroke's sign (tight shirt collar) - ? | |||
==Diagnosis== | ==Diagnosis== | ||
#CXR shows mediastinal mass or paranchymal lung mass in 10% | |||
#CT is diagnostic | |||
CXR shows mediastinal mass or paranchymal lung mass in 10% | |||
CT is diagnostic | |||
==Management== | ==Management== | ||
#Furosemide 40mg IV | |||
#Methylprednisolone 1-2 mg/kg IV | |||
Furosemide 40mg IV | #Mediastinal radiation | ||
Methylprednisolone 1-2 mg/kg IV | |||
Mediastinal radiation | |||
===Source=== | ===Source=== | ||
Sotelo 10/09 | Sotelo 10/09 | ||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
Revision as of 13:23, 15 March 2011
Pathophysiology
- Occurs in 3-8% with lung cancer and lymphoma
- Symptoms due to venous hypertension in areas drained by SVC
- Deaths occurs from cerebral edema, airway compromise, or cardiac compromise
Clinical features
- Thoracic or neck vein distention - 65%
- Shortness of breath - 50%
- Tachypnea - 40%
- Upper trunk or extremity edema - 40%
- Cough/dysphagia/chest pain - 20%
- Peri-orbital or facial edema - ?
- Stroke's sign (tight shirt collar) - ?
Diagnosis
- CXR shows mediastinal mass or paranchymal lung mass in 10%
- CT is diagnostic
Management
- Furosemide 40mg IV
- Methylprednisolone 1-2 mg/kg IV
- Mediastinal radiation
Source
Sotelo 10/09