Goodpasture syndrome: Difference between revisions
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==Background== | ==Background== | ||
*Goodpasture syndrome: diffuse pulmonary hemorrhage + acute glomerulonephritis. | |||
*Goodpasture disease: glomerulonephritis +/-pulmonary hemorrhage, + anti–glomerular basement membrane (anti-GBM) antibodies. *Anti-GBM disease is most precise term for both entities. | |||
**Type II hypersensitivty causing linear IG deposition in glomerular and alveolar BM. | |||
**Triggered by:Sepsis, URI, inhalation injury, smoking, pulmonary edema. | |||
==Clinical Features== | ==Clinical Features== | ||
Revision as of 03:43, 24 January 2016
Background
- Goodpasture syndrome: diffuse pulmonary hemorrhage + acute glomerulonephritis.
- Goodpasture disease: glomerulonephritis +/-pulmonary hemorrhage, + anti–glomerular basement membrane (anti-GBM) antibodies. *Anti-GBM disease is most precise term for both entities.
- Type II hypersensitivty causing linear IG deposition in glomerular and alveolar BM.
- Triggered by:Sepsis, URI, inhalation injury, smoking, pulmonary edema.
Clinical Features
Differential Diagnosis
Diagnosis
Management
- See Hemoptysis