Goodpasture syndrome: Difference between revisions

Revision as of 03:46, 24 January 2016

Goodpasture syndrome (60%): diffuse pulmonary hemorrhage + acute glomerulonephritis.
Goodpasture disease: glomerulonephritis alone (30%,) pulmonary sx alone (10%,)
Anti-GBM disease is most precise term for both entities.
- Type II hypersensitivty causing linear IG deposition in glomerular and alveolar BM.
- Triggered by:Sepsis, URI, inhalation injury, smoking, pulmonary edema.

Authors:

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 ==Background==
-*Goodpasture syndrome: diffuse pulmonary hemorrhage + acute glomerulonephritis.
+*Goodpasture syndrome (60%): diffuse pulmonary hemorrhage + acute glomerulonephritis.
-*Goodpasture disease: glomerulonephritis +/-pulmonary hemorrhage, + anti–glomerular basement membrane (anti-GBM) antibodies. *Anti-GBM disease is most precise term for both entities.
+*Goodpasture disease: glomerulonephritis alone (30%,) pulmonary sx alone (10%,)
+*Anti-GBM disease is most precise term for both entities.
 **Type II hypersensitivty causing linear IG deposition in glomerular and alveolar BM.
 **Triggered by:Sepsis, URI, inhalation injury, smoking, pulmonary edema.