Intravascular hemolytic tranfusion reaction: Difference between revisions

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===Intravascular Hemolytic Tranfusion Reaction===
*Occurs due to ABO incompatibility
*Diagnosis
**Back pain, headache, hypotension, dyspnea, pulmonary edema, bleeding, renal failure
**Labs c/w hemolysis
*Treatment
**Stop transfusion
**Replace all tubing
***Risk of death is proportional to amount of incompatible blood received
**Maintain urine output with IVF (1-2 mL/kg/hr), mannitol, and furosemide as needed
**Treat shock with volume and vasopressors
**Treat coagulopathy w/ FFP

Revision as of 20:46, 4 February 2016

Background

Clinical Features

Differential Diagnosis

Transfusion Reaction Types

Diagnosis

Management

Disposition

See Also

External Links

References


Intravascular Hemolytic Tranfusion Reaction

  • Occurs due to ABO incompatibility
  • Diagnosis
    • Back pain, headache, hypotension, dyspnea, pulmonary edema, bleeding, renal failure
    • Labs c/w hemolysis
  • Treatment
    • Stop transfusion
    • Replace all tubing
      • Risk of death is proportional to amount of incompatible blood received
    • Maintain urine output with IVF (1-2 mL/kg/hr), mannitol, and furosemide as needed
    • Treat shock with volume and vasopressors
    • Treat coagulopathy w/ FFP