Intravascular hemolytic tranfusion reaction: Difference between revisions
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==Background== | ==Background== | ||
*Occurs due to ABO incompatibility | |||
==Clinical Features== | ==Clinical Features== | ||
*Back pain, headache, hypotension, dyspnea, pulmonary edema, bleeding, renal failure | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
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==Diagnosis== | ==Diagnosis== | ||
*Labs consistent with hemolysis | |||
==Management== | ==Management== | ||
*Stop transfusion | |||
*Replace all tubing | |||
**Risk of death is proportional to amount of incompatible blood received | |||
*Maintain urine output with IVF (1-2 mL/kg/hr), [[mannitol]], and [[furosemide]] as needed | |||
*Treat shock with volume and [[vasopressors]] | |||
*Treat coagulopathy with [[FFP]] | |||
==Disposition== | ==Disposition== | ||
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==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 20:49, 4 February 2016
Background
- Occurs due to ABO incompatibility
Clinical Features
- Back pain, headache, hypotension, dyspnea, pulmonary edema, bleeding, renal failure
Differential Diagnosis
Transfusion Reaction Types
- Acute
- Delayed
Diagnosis
- Labs consistent with hemolysis
Management
- Stop transfusion
- Replace all tubing
- Risk of death is proportional to amount of incompatible blood received
- Maintain urine output with IVF (1-2 mL/kg/hr), mannitol, and furosemide as needed
- Treat shock with volume and vasopressors
- Treat coagulopathy with FFP