Alcohol withdrawal: Outpatient management: Difference between revisions
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*25-50mg of chlordiazepoxide is equivalent to 10mg of diazepam | *25-50mg of chlordiazepoxide is equivalent to 10mg of diazepam | ||
*50mg of chlordiazepoxide every 8 hours for two days, thel decrease to 25mg every 8 hours for another two days followed by 25mg PRN as needed. | *50mg of chlordiazepoxide every 8 hours for two days, thel decrease to 25mg every 8 hours for another two days followed by 25mg PRN as needed. | ||
===Anticonvulsants=== | |||
*[[Gabapentin]] 400mg PO TID<ref>Leung JG, Hall-Flavin D, Nelson S, et al. The role of gabapentin in the management of alcohol withdrawal and dependence. Ann Pharmacother. 2015; 49(8):897-906.</ref> | |||
**Some protocols call for higher dosing - 600 or 800mg x1 | |||
*Similar efficacy to lorazepam in decreasing craving and anxiety<ref>Myrick, H et al. A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal. Alcohol Clin Exp Res. 2009 Sep;33(9):1582-8. PMID: 19485969</ref> | |||
==See Also== | ==See Also== | ||
Revision as of 17:24, 15 February 2016
Management
Chlordiazepoxide
Generally for outpatient treatment of mild cases and as a taper
- 25-50mg of chlordiazepoxide is equivalent to 10mg of diazepam
- 50mg of chlordiazepoxide every 8 hours for two days, thel decrease to 25mg every 8 hours for another two days followed by 25mg PRN as needed.
Anticonvulsants
- Gabapentin 400mg PO TID[1]
- Some protocols call for higher dosing - 600 or 800mg x1
- Similar efficacy to lorazepam in decreasing craving and anxiety[2]
See Also
External Links
References
- ↑ Leung JG, Hall-Flavin D, Nelson S, et al. The role of gabapentin in the management of alcohol withdrawal and dependence. Ann Pharmacother. 2015; 49(8):897-906.
- ↑ Myrick, H et al. A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal. Alcohol Clin Exp Res. 2009 Sep;33(9):1582-8. PMID: 19485969