Cefprozil: Difference between revisions
Ostermayer (talk | contribs) (Text replacement - "Category:Drugs" to "Category:Pharmacology") |
Neil.m.young (talk | contribs) (Text replacement - "* " to "*") |
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==Adult Dosing== | ==Adult Dosing== | ||
Infections, bacterial: | Infections, bacterial: | ||
* 250-500 mg PO q12h x 10 days | *250-500 mg PO q12h x 10 days | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
infections, bacterial: | infections, bacterial: | ||
* 30 mg/kg/day PO divided q12h x 10 days, max 1000 mg/day | *30 mg/kg/day PO divided q12h x 10 days, max 1000 mg/day | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: B | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: B | ||
| Line 23: | Line 23: | ||
==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
* PKU | *PKU | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*anaphylaxis | *anaphylaxis | ||
* seizures | *seizures | ||
*nephrotoxicity | *nephrotoxicity | ||
*leukopenia or thrombocytopenia | *leukopenia or thrombocytopenia | ||
* steven-johnson syndrome | *steven-johnson syndrome | ||
*c-diff associated diarrhea | *c-diff associated diarrhea | ||
===Common=== | ===Common=== | ||
* nausea | *nausea | ||
*diarrhea | *diarrhea | ||
*vomiting | *vomiting | ||
* transaminitis | *transaminitis | ||
*dizziness | *dizziness | ||
* rash | *rash | ||
*eosinophilia | *eosinophilia | ||
==Pharmacology== | ==Pharmacology== | ||
Revision as of 19:40, 4 July 2016
Administration
- Type: antibiotic
- Dosage Forms: PO
- Routes of Administration: PO
- Common Trade Names: Cefzil
Adult Dosing
Infections, bacterial:
- 250-500 mg PO q12h x 10 days
Pediatric Dosing
infections, bacterial:
- 30 mg/kg/day PO divided q12h x 10 days, max 1000 mg/day
Special Populations
- Pregnancy Rating: B
- Lactation risk: probably safe
Renal Dosing
- Adult: CrCl < 30: decrease dose 50%
- Pediatric:CrCl < 30: decrease dose 50%
Hepatic Dosing
- Adult: none defined
- Pediatric: none defined
Contraindications
- Allergy to class/drug
- PKU
Adverse Reactions
Serious
- anaphylaxis
- seizures
- nephrotoxicity
- leukopenia or thrombocytopenia
- steven-johnson syndrome
- c-diff associated diarrhea
Common
- nausea
- diarrhea
- vomiting
- transaminitis
- dizziness
- rash
- eosinophilia
Pharmacology
- Half-life: 1.3 h
- Metabolism: other
- Excretion: urine
Mechanism of Action
bactericidal, inhibits cell wall mucopeptide synthesis