Unfractionated heparin: Difference between revisions

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##[[NSTEMI]]
##[[NSTEMI]]
##[[STEMI]]
##[[STEMI]]
==See Also==
*[[Low Molecular Weight Heparin]]


==Source ==
==Source ==

Revision as of 06:59, 21 October 2011

Background

  • Binds to and activates antithrombin which in turns inactivates factor Xa and thrombin
  • Half-life is 30-150min
  • Must give IV (not subq) for acute thromboembolic disease
  • Safe in pregnancy
  • Unpredictable anticoagulation effect
    • Must monitor w/ PTT; therapeutic range is 1.5-2.5x normal value

Treatment

  1. See:
    1. DVT
    2. PE
    3. NSTEMI
    4. STEMI

See Also

Source

Tintinalli

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