ITP in Pregnancy: Difference between revisions
No edit summary |
|||
| Line 1: | Line 1: | ||
==Background== | ==Background== | ||
*Marked diff between maternal and fetal platelet counts | |||
*No antenatal measures predict fetal status | |||
*Maternal response to medicine does not guarantee a favorable outcome for baby | |||
*Only previous neonatal outcomes provide predictor of neonatal platelet counts. | |||
== | ==Clinical Features== | ||
*Low platelets during pregnancy | |||
==Differential Diagnosis== | |||
*preg induced HTN | |||
*HELLP | |||
*microangiopathic hemolytic anemia | |||
*hereditary | |||
*thrombocytopenias | |||
==Diagnosis== | ==Diagnosis== | ||
*Usually mild thrombocytopenia (>70k) | |||
**Platelet count normalizes after delivery | |||
==Treatment== | ==Treatment== | ||
*Most medications are teratogenic or worsens gestational diabetes (prednisone) so use iv IG mostly | |||
* baby with v low risk of ICH- but higher of normal baby | |||
* risk of ICH not change with cesarean | |||
* if baby with platelets <30k, try iv ig and or prednisone | |||
* exchange xfusion only if severe. | |||
* no problem for breast feeding. | |||
==See Also== | ==See Also== | ||
| Line 30: | Line 31: | ||
==Source== | ==Source== | ||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
[[Category:OB/GYN]] | [[Category:OB/GYN]] | ||
Revision as of 04:40, 6 June 2015
Background
- Marked diff between maternal and fetal platelet counts
- No antenatal measures predict fetal status
- Maternal response to medicine does not guarantee a favorable outcome for baby
- Only previous neonatal outcomes provide predictor of neonatal platelet counts.
Clinical Features
- Low platelets during pregnancy
Differential Diagnosis
- preg induced HTN
- HELLP
- microangiopathic hemolytic anemia
- hereditary
- thrombocytopenias
Diagnosis
- Usually mild thrombocytopenia (>70k)
- Platelet count normalizes after delivery
Treatment
- Most medications are teratogenic or worsens gestational diabetes (prednisone) so use iv IG mostly
- baby with v low risk of ICH- but higher of normal baby
- risk of ICH not change with cesarean
- if baby with platelets <30k, try iv ig and or prednisone
- exchange xfusion only if severe.
- no problem for breast feeding.