Torsemide: Difference between revisions
ClaireLewis (talk | contribs) (Created page with "==Administration== *Type: Loop diuretic *Dosage Forms: *Routes of Administration: IV, PO *Common Trade Names: Demadex ==Adult Dosing== ''40mg furosemide = 20mg torsemide...") |
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==Administration== | ==Administration== | ||
*Type: Loop diuretic | *Type: Loop [[diuretic]] | ||
*Dosage Forms: | *Dosage Forms: | ||
*Routes of Administration: IV, PO | *Routes of Administration: IV, PO | ||
Revision as of 09:11, 24 September 2016
Administration
- Type: Loop diuretic
- Dosage Forms:
- Routes of Administration: IV, PO
- Common Trade Names: Demadex
Adult Dosing
40mg furosemide = 20mg torsemide = 1mg bumetanide
- 5-200 mg PO or IV daily. Titrate to effect by doubling dose
Pediatric Dosing
Safety/efficacy not established
Special Populations
- Pregnancy Rating: B
- Lactation risk: Infant risk cannot be ruled out
Renal dosing: no adjustment Hepatic dosing: no adjustment
Contraindications
- Allergy to class/drug
- Anuria
Adverse Reactions
Serious
- Ventricular tachycardia
- SJS/TEN
- Ototoxicity
Common
- Polyuria
- Rhinitis
Pharmacology
- Half-life: 2-4 hours
- Metabolism: P450
- Excretion: Renal
Mechanism of Action
- Loop diuretic: interferes with Na/K/Cl cotransport system, inhibiting reabsorption of Na/Cl in the ascending limb of the loop of Henle