SNRI Toxicity: Difference between revisions

(Created page with "==Background== *Inhibit reuptake of serotonin and norepinephrine (venlafaxine, duloxetine) *Although produce more symptoms in overdose compared to SSRIs, still extremely safe ==C...")
 
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*Admit all symptomatic pts to a monitored bed
*Admit all symptomatic pts to a monitored bed
*All pts require at least 6hr of observation
*All pts require at least 6hr of observation
==See Also==
*[[SSRI Toxicity]]


==Source==
==Source==

Revision as of 20:47, 21 November 2012

Background

  • Inhibit reuptake of serotonin and norepinephrine (venlafaxine, duloxetine)
  • Although produce more symptoms in overdose compared to SSRIs, still extremely safe

Clinical Features

  • Sympathomimetic: tachycardia, hypertension, diaphoresis, tremor, mydriasis
  • Sedation
  • Seizure
  • ECG
    • Sinus tachycardia

Treatment

  1. GI decontamination
    1. Activatec charcoal x1

Disposition

  • Admit all symptomatic pts to a monitored bed
  • All pts require at least 6hr of observation

See Also

Source

  • Tintinalli