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| ==Evaluation==
| | #REDIRECT[[Syndrome of Inappropriate Antidiuretic Hormone Secretion]] |
| ===Essential Criteria<ref>Schwartz WB, Bennett W, Curelop S, Bartter FC. A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. American Journal of Medicine 1957 23 529–542</ref>===
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| *Effective serum osmolality <275 mOsm/kg
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| *Urine osmolality >100 mOsm/kg at some level of decreased effective osmolality
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| *Clinical euvolaemia
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| *Urine sodium concentration >30 mmol/l with normal dietary salt and water intake
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| *Absence of adrenal, thyroid, pituitary or renal insufficiency
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| *No recent use of diuretic agents
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| ===Supplemental criteria===
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| *Serum uric acid <0.24 mmol/l (<4mg/dl)
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| *Serum urea <3.6 mmol/l (<21.6mg/dl)
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| *Failure to correct hyponatraemia after 0.9% saline infusion
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| *Fractional sodium excretion >0.5%
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| *Fractional urea excretion >55%
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| *Fractional uric acid excretion >12%
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| *Correction of hyponatraemia through fluid restriction
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| ==Etiology==
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| *Extensive differential to include categories in CNS disorders, neoplastic, pulmonary, drug-induced
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| *See more here - [http://emedicine.medscape.com/article/246650-overview#a5 eMedicine, etiologies]
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| ==References==
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| <references/>
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| [[Category:FEN]] | |
