Alpha blockers: Difference between revisions
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==Background== | ==Background== | ||
*Also known as α-blockers | *Also known as α-blockers | ||
**& | **&α;<sub>1</sub>-blockers act on &α;<sub>1</sub>-adrenoceptors | ||
**& | **&α;<sub>2</sub>-blockers act on &α;<sub>2</sub>-adrenoceptors | ||
*Act as neutral antagonists or inverse agonists of & | *Act as neutral antagonists or inverse agonists of &α;-adrenergic receptors (α-adrenoceptors) | ||
==Medications== | ==Medications== | ||
Revision as of 01:12, 24 July 2017
Background
- Also known as α-blockers
- &α;1-blockers act on &α;1-adrenoceptors
- &α;2-blockers act on &α;2-adrenoceptors
- Act as neutral antagonists or inverse agonists of &α;-adrenergic receptors (α-adrenoceptors)
Medications
Non-selective
- Phenoxybenzamine
- Phentolamine
- Tolazoline
- Trazodone
- Typical and atypical antipsychotics
Selective Alpha 1
Selective Alpha 2
Mixed
- The agents carvedilol and labetalol are both α- and β-blockers.
Uses
- hypertension
- Raynaud's disease
- scleroderma
- generalized anxiety disorder
- panic disorder
- posttraumatic stress disorder
- benign prostatic hyperplasia