Hypokalemia: Difference between revisions

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*Shift
*Shift
**Alkalosis (each 0.10 rise in pH causes 0.5 decrease)
**Alkalosis (each 0.10 rise in pH causes 0.5 decrease)
**Insulin
**[[Insulin]]
**B-agonist
**B-agonist
*Decreased intake
*Decreased intake
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***Hyperaldo
***Hyperaldo
**Exercise
**Exercise
***HyperCa
***[[HyperCa]]
***HypoMg
***[[HypoMg]]
*Drugs
*Drugs
**PCN
**PCN
**Lithium
**[[Lithium]]
**L-dopa
**L-dopa
**Theophyline
**Theophyline

Revision as of 07:08, 18 December 2013

Background

  • Low = <3.5meq/L
  • Low! = <2.5meq/L

Clinical Features

  • CNS
    • Weakness
    • Cramps
    • Hyporeflexia
  • GI
    • Ileus
  • Renal
    • Met alkalosis
  • CV
    • PACs/PVCs
    • Bradycardia or atrial/junctional tachycardia
    • AV block
    • V tach, V fib

Diagnosis

  • ECG findings:
    • ST seg depression
    • U wave (V4-V6)
    • QT prolongation

ECG Hypokalemia.jpg

DDX

  • Shift
    • Alkalosis (each 0.10 rise in pH causes 0.5 decrease)
    • Insulin
    • B-agonist
  • Decreased intake
  • Increased loss
    • GI (v/d/fistula)
    • Renal
      • Diuretics
      • Hyperaldo
    • Exercise
  • Drugs

Treatment

  • 20meq/hr KCl IV or PO
    • every 10meq should inc serum by ~0.1meq/L
  • Treat hypomag if present
  • Usual dose is 40meq IV or PO unless level is <2.5. If so, both forms should be given
  • 10meq will raise serum level by 0.1
  • Intravenous K+ typically runs at 10meq/hour, burns when infused, and may cause phelbitis/sclerosis if run faster
  • Oral K+ more quickly absorbed and preferred
  • KCl elixir easily swallowed, but tastes terrible, KDur oral tablet is large and hard to swallow

See Also

Electrolyte Abnormalities (Main)

Source

  • Tintinalli