Metabolic syndrome: Difference between revisions
| Line 16: | Line 16: | ||
BP >/= 130/85 or requiring drug treatment for HTN <ref name="UpToDate">[https://www.uptodate.com/contents/the-metabolic-syndrome-insulin-resistance-syndrome-or-syndrome-x?source=search_result&search=metabolic%20syndrome%20adult&selectedTitle=1~150].</ref><br /> | BP >/= 130/85 or requiring drug treatment for HTN <ref name="UpToDate">[https://www.uptodate.com/contents/the-metabolic-syndrome-insulin-resistance-syndrome-or-syndrome-x?source=search_result&search=metabolic%20syndrome%20adult&selectedTitle=1~150].</ref><br /> | ||
'''Additional Markers'''<br /> | '''Additional Markers'''<br /> | ||
MSX is considered to be a prothrombotic, proimflammatory state. As such, it may be associated with elevated CRP, IL-6 and tissue plasminogen activator. The elevated inflammatory markers may be associated with increased risk for CVD and Type 2 Diabetes Mellitus. However, these markers have not been shown of any benefit in the ED. Rather, they should be used for evaluation of risk of CVD in the outpatient setting | MSX is considered to be a prothrombotic, proimflammatory state. As such, it may be associated with elevated CRP, IL-6 and tissue plasminogen activator. The elevated inflammatory markers may be associated with increased risk for CVD and Type 2 Diabetes Mellitus. However, these markers have not been shown of any benefit in the ED. Rather, they should be used for evaluation of risk of CVD in the outpatient setting.<ref name="UTD reference 2">[https://www.uptodate.com/contents/the-metabolic-syndrome-insulin-resistance-syndrome-or-syndrome-x/abstract/41]</ref> | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revision as of 14:18, 26 August 2017
Background
- Three or more of the following or if taking any medication to control disease.
- Large waist circumference — At least 35 inches (89 centimeters) for women and 40 inches for men
- High triglyceride level — 150 mg/dL or 1.7 mmol/L
- Reduced high-density lipoprotein (HDL) cholesterol — less than 40 mg/dL (1.04 mmol/L) in men or less than 50 mg/dL (1.3 mmol/L) in women of this "good" cholesterol
- Increased blood pressure — 130/85 or higher
- Elevated fasting blood sugar — 100 mg/dL or higher
Clinical Features
Diagnostic Criteria
Waist circumference >/=102 cm in men or >/=88 cm in women
Plus 3 of the following:
Fasting blood glucose >/= to 100 mg/dL or requiring treamtment for elevated blood glucose
HDL </=40 in men or </=50 in women
TGs >/=150 mg/dL
BP >/= 130/85 or requiring drug treatment for HTN [1]
Additional Markers
MSX is considered to be a prothrombotic, proimflammatory state. As such, it may be associated with elevated CRP, IL-6 and tissue plasminogen activator. The elevated inflammatory markers may be associated with increased risk for CVD and Type 2 Diabetes Mellitus. However, these markers have not been shown of any benefit in the ED. Rather, they should be used for evaluation of risk of CVD in the outpatient setting.[2]
Differential Diagnosis
Evaluation
Management
Disposition
See Also
References
1. Grundy, S. M. (2005). Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement: Executive Summary. Circulation, 112(17). doi:10.1161/circulationaha.105.169405
2. Genuth, S. (2003). Follow-up report on the diagnosis of diabetes mellitus. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus , 26(11). Retrieved from https://www.ncbi.nlm.nih.gov/pubmed?term=14578255.