Local anesthetic systemic toxicity: Difference between revisions
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***Asystole | ***Asystole | ||
==Management== | |||
*Lipid emulsion | *Lipid emulsion | ||
**1.5 mL/kg bolus over 1 minute | **1.5 mL/kg bolus over 1 minute | ||
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==See Also== | ==See Also== | ||
[[Lidocaine]] | *[[Lidocaine]] | ||
*[[Nerve Blocks (Main)]] | |||
[[Category:Tox]] | [[Category:Tox]] | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 07:30, 3 January 2014
Background
- Complication of lidocaine injection (accidental into systemic circulation)
- 0.2% of nerve blocks
- Occurs within minutes of injection
- 75% occuring within 5 minutes
Diagnosis
- CNS symptoms
- Agitation
- Auditory changes
- Metallic taste
- Seizures or drowsiness
- Coma
- Respiratory arrest
- Cardiovascular
- First excitation
- Tachycardia
- Ventricular dysrhythmia
- Hypertension
- Followed by depression
- Bradycardia
- Conduction block
- Asystole
- First excitation
Management
- Lipid emulsion
- 1.5 mL/kg bolus over 1 minute
- Then, 15 mL/kg per hour x 20-minute infusion