Anion gap: Difference between revisions
(Joining high and low anion gap pages into a single entry to streamline access to info) |
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*AG falls by 2.5 meq/L for every 1 g/dL reduction in albumin concentration | *AG falls by 2.5 meq/L for every 1 g/dL reduction in albumin concentration | ||
==See Also== | |||
[[Anion Gap and Osmolar Gap (High)]] | |||
==Source== | |||
Kaji Questions | |||
MISTRY 6/06 | |||
[[Category:FEN]] | |||
[[Category:Tox]] | |||
Revision as of 16:03, 7 February 2014
Elevated Anion Gap
DDx
MUDPILES
- M - Methanol
- U - Uremia
- D - DKA
- P - Paraldehyde
- I - Iron, INH
- L - Lactic acidosis
- E - Ethylene glycol
- S - Salicylates
Also:
- Starvation/ETOH ketoacidosis
- CO, CN poisoning (incr. lactate)
Low Anion Gap
Background
- < 7 meq/L
DDX
- Lab error
- Decreased "unmeasured" anions
- hypoalbuminemia
- Increased "unmeasured" cations
- Increased cationic paraprotein
- Multiple myeloma
- Polyclonal IgG gammopathy
- Pseudo
- Severe Hypernatremia (>170 meq/L)
- True conc of Na is underestimated
- Marked hyperlipidemia
- Leads to overestimation of plasma Cl conc)
- Bromide intoxication (e.g. for myasthenia gravis and some herbal medications)
- Machine mistakenly reads Br as Cl
- Severe Hypernatremia (>170 meq/L)
- AG falls by 2.5 meq/L for every 1 g/dL reduction in albumin concentration
See Also
Anion Gap and Osmolar Gap (High)
Source
Kaji Questions MISTRY 6/06