Physostigmine: Difference between revisions
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==General== | ==General== | ||
*Type: [[acetylcholinesterase inhibitor]] | *Type: [[acetylcholinesterase inhibitor]] | ||
*Dosage Forms: | *Dosage Forms: IV/IM | ||
*Common Trade Names: | *Common Trade Names: Antilirium | ||
==Adult Dosing== | ==Adult Dosing== | ||
Revision as of 19:51, 7 October 2018
General
- Type: acetylcholinesterase inhibitor
- Dosage Forms: IV/IM
- Common Trade Names: Antilirium
Adult Dosing
Anticholinergic toxicity
- 0.5-2mg IV over 5min
Pediatric Dosing
- .02mg/kg repeat every 5-10 minutes until adequate response, max of 2mg
- no faster than .5mg/min
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
- Side effects: bradycardia, dysrhythmias, cholinergic excess
- Always have atropine at the bedside for bradycardia or cholinergic excess
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
- Onset of action: 15-20min