Whole bowel irrigation: Difference between revisions

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==Indications<ref>Thanacoody, R, et al. Position paper update: Whole bowel irrigation for gastrointestinal decontamination of overdose patients. Clin Toxicol. 2015; 53(1):5-12. doi: 10.3109/15563650.2014.989326.</ref>==
==Indications<ref>Thanacoody, R, et al. Position paper update: Whole bowel irrigation for gastrointestinal decontamination of overdose patients. Clin Toxicol. 2015; 53(1):5-12. doi: 10.3109/15563650.2014.989326.</ref>==
*Sustained or delayed-release formulations
*'''''LIMPS''' = '''L'''ithium, '''I'''ron, '''M'''etals, '''P'''ackers/stuffer, '''S'''ustained release drugs (especially beta-blockers, calcium channel blockers)
*Agents with potential for bezoar formation
**[[Lithium overdose]] (extended-release tablets)
*Iron and other heavy metals
**Iron
*Paint chips containing [[Lead]]
**Heavy metals
*[[Lithium overdose]] (extended-release tablets)
**Toxic ingestions of sustained- or delayed-release formulations
*Drugs carried by body packers
**Drugs carried by body packers
*'''''LIMPS''' = '''L'''ithium, '''I'''ron, '''M'''etals, '''P'''ackers/stuffer, '''S'''ustained release drugs (BB, CCB)
*Additional considerations:
*Be mindful that the addition of PEG to activated charcoal significantly decreases AC's adsorptive capacity
**Agents that cause bezoar or concretion formation
**likely competes with xenobiotic for adsorption by AC
**Paint chips containing [[lead]]
*Be mindful that the addition of PEG to activated charcoal significantly decreases activated charcoal's adsorptive capacity


==Contraindications==
==Contraindications==

Revision as of 01:17, 14 May 2019

Indications[1]

  • LIMPS = Lithium, Iron, Metals, Packers/stuffer, Sustained release drugs (especially beta-blockers, calcium channel blockers)
    • Lithium overdose (extended-release tablets)
    • Iron
    • Heavy metals
    • Toxic ingestions of sustained- or delayed-release formulations
    • Drugs carried by body packers
  • Additional considerations:
    • Agents that cause bezoar or concretion formation
    • Paint chips containing lead
  • Be mindful that the addition of PEG to activated charcoal significantly decreases activated charcoal's adsorptive capacity

Contraindications

  • Preceding diarrhea
  • Ingestion of substances expected to result in significant diarrhea (except heavy metals)
  • Bowel obstruction (as evidenced by lack of bowel sounds)
  • avoid chilled solutions in neonates given risk for hypothermia

Procedure

  • Give polyethylene glycol via NGT or PO (if tolerates) until rectal effluent is clear
    • Adult: 1.5-2 L/hr
    • Peds 6-12yr: 1 L/hr
    • Peds <6yr: 0.5 L/hr
    • Peds alt: 20-40 mL/kg/hr in young children

Give ondansteron or metoclopramide as needed for nausea/vomiting

Complications

  • Bloating
  • Cramping
  • Rectal irritation (from frequent bowel movements)

See Also

References

  1. Thanacoody, R, et al. Position paper update: Whole bowel irrigation for gastrointestinal decontamination of overdose patients. Clin Toxicol. 2015; 53(1):5-12. doi: 10.3109/15563650.2014.989326.