Soil-transmitted helminthes: Difference between revisions

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==Background==
*[[Ascaris]]
 
*[[Whipworm]]
==Clinical Features==
*[[Hookworm]]
*Includes Ascaris roundworm, whipworm, and hookworms
*Morbidity is related to number of worms harbored in intestines
*Light infections often asymptomatic
*Heavier infections with variety of manifestations including GI symptoms (abdominal pain, diarrhea, blood in stool, rectal prolapse), malaise, weakness, impaired cognitive / physical development, malnutrition<ref>Wilcox S, Thomas S, Brown D, Nadel E.  “Gastrointestinal Parasite.”  The Journal of Emergency Medicine, 2007; 33(3):277-280</ref></ref>
*Hookworm and whipworm infestations also cause iron-deficiency anemia
**Adult worms attach to intestinal wall to feed, causing ongoing luminal blood loss
*'''Löffler’s syndrome'''
**Result of Ascaris or hookworm larval transit through the lungs
**Characterized by persistent non-productive cough, chest pain, wheezing, rales, pulmonary infiltrates on CXR and marked eosinophilia
 
==Differential Diagnosis==
 
==Workup==
 
==Management==
*[[Ascaris]]: albendazole 400 mg x 1 dose OR mebendazole 100 mg BID x 3 days (both high efficacy)
 
*[[Whipworm]] (Trichuris): albendazole 400 mg x 1 dose
**Historically treated with albendazole or mebendazole, but monotherapy has low efficacy against Trichuris especially in heavy infections; higher cure rate achieved with oxantel pamoate-albendazole combination compared to any monotherapy in recent RCT <ref>Speich B, Ame S, et al. "Oxantel Pamoate–Albendazole for Trichuris Trichiura Infection." New England Journal of Medicine, 2014; 370: 610-620.</ref>
 
*[[Hookworm]]: albendazole 400 mg x 1 dose (high efficacy) OR mebendazole 500 mg x 1 dose (low to moderate efficacy)
 
*Iron supplements in [[anemia]]
 
==Disposition==


==See Also==
==See Also==
*[[Worm Infections]]
*[[Worm Infections]]
*[[Travel Medicine]]
*[[Travel Medicine]]
==External Links==
==Sources==
<references/>


[[Category:ID]]
[[Category:ID]]
[[Category:TropMed]]
[[Category:TropMed]]

Revision as of 20:04, 7 September 2014