Template:Cervicitis Urethritis Antibiotics: Difference between revisions

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''Treatment covers both [[gonorrhea]] and [[chlamydia]]''
====Presumed [[GC]]/[[chlamydia]] of cervix, urethra, or rectum (uncomplicated)<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>====
====Uncomplicated Infection====
''Typically, treatment for '''both''' gonorrhea and chlamydia is indicated, if one entity is suspected.''<br>
*[[Ceftriaxone]] 500mg IM once PLUS
<br>
**[[Doxycycline]] 100mg PO BID x 14 days (7 days for gonorrhea, 14 days for chlamydia)<ref>2020 CDC update</ref>
<u>Standard</u><br>
*Gonorrhea
**[[Ceftriaxone]] IM x 1
***500 mg, if weight <150 kg
***1 g, if weight ≥150 kg
*Chlamydia
**Nonpregnant: [[doxycycline]] 100 mg PO BID x 7 days
**Pregnant: [[azithromycin]] 1 g PO x 1


====Cephalosporin Allergy====
<br>
*[[Azithromycin]] 2g PO once PLUS
<u>Ceftriaxone contraindicated</u><br>
**[[Gentamicin]] 240mg IM once<ref>[http://www.cdc.gov/std/tg2015/ CDC: 2015 Sexually Transmitted Diseases Treatment Guidelines]</ref>
*Gonorrhea
**In theory this high dose macrolide will provide treatment for both [[GC]] and [[Chlamydia]]
**[[Gentamicin]] 240 mg IM x 1 '''PLUS''' [[azithromycin]] 2 g PO x 1, '''OR'''
**[[Cefixime]] 800 mg PO x 1
*Chlamydia^
**Nonpregnant: [[doxycycline]] 100 mg PO BID x 7 days
**Pregnant: [[azithromycin]] 1 g PO x 1


====Partner treatment====
^Additional chlamydia coverage only needed if treated with cefixime only
*[[Cefixime]] 400mg PO once PLUS
 
**[[Azithromycin]] 1g PO once OR
====Partner Treatment====
**[[Doxycycline]] 100mg PO BID x 7 days
*Gonorrhea
**[[Cefixime]] 800mg PO x 1
*Chlamydia
**Nonpregnant: [[doxycycline]] 100mg PO BID x 7 days, '''OR'''
**Pregnant: [[azithromycin]] 1g PO x 1


====Associated [[Bacterial Vaginosis]] or [[Trichomonas vaginalis]]====
====Associated [[Bacterial Vaginosis]] or [[Trichomonas vaginalis]]====
{{Trichomonas antibiotics}}
{{Trichomonas antibiotics}}

Revision as of 18:58, 23 December 2020

Presumed GC/chlamydia of cervix, urethra, or rectum (uncomplicated)[1]

Typically, treatment for both gonorrhea and chlamydia is indicated, if one entity is suspected.

Standard

  • Gonorrhea
    • Ceftriaxone IM x 1
      • 500 mg, if weight <150 kg
      • 1 g, if weight ≥150 kg
  • Chlamydia


Ceftriaxone contraindicated

^Additional chlamydia coverage only needed if treated with cefixime only

Partner Treatment

Associated Bacterial Vaginosis or Trichomonas vaginalis

Non-Pregnant

Pregnant

Only treat if the patient is symptomatic

Sexual Partner Treatment

  1. Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916
  2. Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep 2021;70(No. RR-4):1–187. DOI: http://dx.doi.org/10.15585/mmwr.rr7004a1external icon
  3. CDC Trichomoniasis 2021. https://www.cdc.gov/std/treatment-guidelines/trichomoniasis.htm
  4. Workowski KA, Bachmann LH, Chan PA, et al. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep 2021;70(No. RR-4):1–187. DOI: http://dx.doi.org/10.15585/mmwr.rr7004a1external icon