Neuroblastoma (peds): Difference between revisions
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==Background== | ==Background== | ||
*Arises from primitive ganglion cells of sympathetic nervous system | |||
*Most common neoplasm in 1st yr of life | |||
*May arise anywhere along sympathetic nervous system | |||
**Adrenal gland (40%) | |||
**Abdomen (25%) | |||
**Chest (15%) | |||
==Diagnosis== | ==Diagnosis== | ||
*Depends on location | |||
**Large, painless abdominal mass | |||
**Compression of bowel/bladder | |||
**Horner syndrome | |||
**Spinal cord compression | |||
*Opsoclonus-myoclonus | |||
**Highly a/w neuroblastoma | |||
*Neutropenia/pancytopenia suggests bone marrow involvement | |||
==Work-Up== | ==Work-Up== | ||
*CXR | |||
==Treatment== | ==Treatment== | ||
*Admssion for tumor biopsy | |||
==Source== | ==Source== | ||
Tintinalli | |||
[[Category:Peds]] | [[Category:Peds]] | ||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
Revision as of 23:10, 29 June 2011
Background
- Arises from primitive ganglion cells of sympathetic nervous system
- Most common neoplasm in 1st yr of life
- May arise anywhere along sympathetic nervous system
- Adrenal gland (40%)
- Abdomen (25%)
- Chest (15%)
Diagnosis
- Depends on location
- Large, painless abdominal mass
- Compression of bowel/bladder
- Horner syndrome
- Spinal cord compression
- Opsoclonus-myoclonus
- Highly a/w neuroblastoma
- Neutropenia/pancytopenia suggests bone marrow involvement
Work-Up
- CXR
Treatment
- Admssion for tumor biopsy
Source
Tintinalli