Template:Appendicitis Antibiotics: Difference between revisions
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====Pediatric Simple Appendicitis==== | ====Pediatric Simple Appendicitis==== | ||
'''Options:''' | |||
*[[Cefoxitin]] 40mg/kg IV q6 hours | *[[Cefoxitin]] 40mg/kg IV q6 hours | ||
*[ | *[[Cefotetan]] 40mg/kg IV q12 hours | ||
*[[Gentamicin]] 2.5mg/kg IV q8hrs + | *[[Gentamicin]] 2.5mg/kg IV q8hrs + | ||
**[[Metronidazole]] 7.5mg/kg IV 16hrs OR | **[[Metronidazole]] 7.5mg/kg IV 16hrs OR | ||
Revision as of 20:12, 14 April 2015
Coverage should extend to E. coli, Klebsiella, Proteus, and Bacteroides (an anaerobe)
Adult Simple Appendicitis
Antibiotic prophylaxis should be coordinated with surgical consult Options:
- Cefoxitin 2g IV q6 hours OR
- Cefotetan 2g IV q12 hours OR
- Moxifloxacin 400mg IV once daily
- Ertapenem 1g IV once daily
Pediatric Simple Appendicitis
Options:
- Cefoxitin 40mg/kg IV q6 hours
- Cefotetan 40mg/kg IV q12 hours
- Gentamicin 2.5mg/kg IV q8hrs +
- Metronidazole 7.5mg/kg IV 16hrs OR
- [[Clindamycin 10mg/kg IV q8hrs
=Complicated Appendicitis
Defined as perforation, abscess, or phlegmon Options:
- Metronidazole 50mg IV q8hrs +
- Cefepime 50mg/kg IV q12hrs OR
- Ciprofloxacin 400mg IV q12hrs OR
- Levofloxacin 750mg IV q24hrs
- Aztreoname 30mg/kg IV q8hrs
Cautious use should be applied to use of fluoroquinolones in complicated pediatric appendicitis due to the risk of tendon injury