Hodgkin's lymphoma: Difference between revisions

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*Survival >90% in low-risk pts
*Survival >90% in low-risk pts


== Diagnosis ==
==Clinical Features==
*Painless, firm, lymph node (usually cervical or supraclavicular)  
*Painless, firm, lymph node (usually cervical or supraclavicular)  
*"B" symptoms: fever, night sweats, wt loss
*"B" symptoms: fever, night sweats, wt loss
== Work-Up ==
*CXR
*CT neck/C/A/P
*LN biopsy


== Differential Diagnosis ==
== Differential Diagnosis ==
Cervical lymphadenopathy  
Cervical lymphadenopathy  


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#Cat scratch disease  
#Cat scratch disease  
#Mycobacterial adenitis
#Mycobacterial adenitis
==Diagnosis==
*CXR
*CT neck/C/A/P
*LN biopsy


== Treatment ==
== Treatment ==

Revision as of 19:41, 11 May 2015

Background

  • Spreads from source lymph node to adjacent nodes
  • Bimodal distribution: young adulthood and older aged
  • Most common malignancy between ages of 15-19 yo
  • Survival >90% in low-risk pts

Clinical Features

  • Painless, firm, lymph node (usually cervical or supraclavicular)
  • "B" symptoms: fever, night sweats, wt loss

Differential Diagnosis

Cervical lymphadenopathy

  1. Non-Hodgkin lymphoma
  2. Mononucleosis
  3. Toxoplasmosis
  4. Branchial cleft lesions
  5. Cat scratch disease
  6. Mycobacterial adenitis

Diagnosis

  • CXR
  • CT neck/C/A/P
  • LN biopsy

Treatment

  • Manage acute complications
    • Superior vena cava syndrome
    • Upper airway compression
      • Do NOT give steroids

See Also

References