Template:Pertussis Antibiotics: Difference between revisions

Revision as of 20:58, 19 March 2026

Antibiotics do not help with severity or duration but may decrease infectivity.
A reasonable guideline is to treat persons aged >1 year within 3 weeks of cough onset and infants aged <1 year and pregnant women (especially near term) within 6 weeks of cough onset. ^[1]
TMP--SMZ should not be administered to pregnant women, nursing mothers, or infants aged <2 months.^[2]
The following regemins are for active disease or postexposure prophylaxis. If a patient is has confirmed disease and is likely to be in contact with infants or pregnant women then the patient should be treated as up to 6-8 weeks after the onset of their illness.

< 1 month old

Same antibiotics for active disease and postexposure prophylaxis

Azithromycin 10mg/kg (max 500mg/day) daily x 5 days

>1 month old

Azithromycin 10mg/kg (max 500mg/day) daily x 5 days
- if > 6 months old then day 2-5 of treatment should be reduced to 5mg/kg (250mg/day max)
TMP/SMX 4mg/kg PO BID daily for 14 days (if > 2 months old)

Adults

any of the following antibiotics are acceptable although azithromycin is most commonly prescribed

Azithromycin 500mg PO once daily for day #1 then 250mg PO once daily for days #2-5
Clarithromycin 500mg BID x7 days
Erythromycin 500mg QID x7 days

↑ CDC - Pertussis http://www.cdc.gov/pertussis/clinical/treatment.html
↑ CDC MMWR Pertusis http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5414a1.htm

[1] CDC - Pertussis http://www.cdc.gov/pertussis/clinical/treatment.html

[2] CDC MMWR Pertusis http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5414a1.htm

[1]

[2]

@@ Line 2: / Line 2: @@
 *A reasonable guideline is to treat persons aged >1 year within 3 weeks of cough onset and infants aged <1 year and pregnant women (especially near term) within 6 weeks of cough onset. <ref>CDC - Pertussis http://www.cdc.gov/pertussis/clinical/treatment.html</ref>
 *TMP--SMZ should not be administered to pregnant women, nursing mothers, or infants aged <2 months.<ref> CDC MMWR Pertusis http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5414a1.htm</ref>
-*The following regemins are for active disease or postexposure prophylaxis.  If a patient is has confirmed disease and is likely to be in contact with infants or pregnant women then the patient should be treated as up to 6-8 weeks after the onset of their illness.
+*The following regemins are for active disease or postexposure prophylaxis. If a patient is has confirmed disease and is likely to be in contact with infants or pregnant women then the patient should be treated as up to 6-8 weeks after the onset of their illness.
 ====< 1 month old====
 ''Same antibiotics for active disease and postexposure prophylaxis''
-*[[Azithromycin]] 10mg/kg (max 500mg/day) daily x 5 days
+*{{AntibioticDose|drug=Azithromycin|dose=10mg/kg (max 500mg/day) daily x 5 days|context=<1 month old|population=Pediatric}}
 ====>1 month old====
-*[[Azithromycin]] 10mg/kg (max 500mg/day) daily x 5 days
+*{{AntibioticDose|drug=Azithromycin|dose=10mg/kg (max 500mg/day) daily x 5 days|context=>1 month old|population=Pediatric}}
 **if > 6 months old then day 2-5 of treatment should be reduced to 5mg/kg (250mg/day max)
-*[[TMP/SMX]] 4mg/kg PO BID daily for 14 days (if > 2 months old)
+*{{AntibioticDose|drug=TMP/SMX|dose=4mg/kg PO BID daily for 14 days|context=>1 month old (if >2mo)|population=Pediatric}} (if > 2 months old)
 ====Adults====
 ''any of the following antibiotics are acceptable although azithromycin is most commonly prescribed''
-*[[Azithromycin]] 500mg PO once daily for day #1 then 250mg PO once daily for days #2-5
+*{{AntibioticDose|drug=Azithromycin|dose=500mg PO once daily for day #1 then 250mg PO once daily for days #2-5|context=Adults}}
-*[[Clarithromycin]] 500mg BID x7 days
+*{{AntibioticDose|drug=Clarithromycin|dose=500mg BID x7 days|context=Adults}}
-*[[Erythromycin]] 500mg QID x7 days
+*{{AntibioticDose|drug=Erythromycin|dose=500mg QID x7 days|context=Adults}}