Lymphatic filariasis: Difference between revisions
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*Also known as elephantiasis | *Also known as elephantiasis | ||
*Causative agents: | *Causative agents: | ||
**Wuchereria bancrofti | **''Wuchereria bancrofti'' | ||
**Brugia malayi | **''Brugia malayi'' | ||
**Brugia timori | **''Brugia timori'' | ||
*Larvae migrate to lymphatic vessels and mature into adults | |||
==Clinical Features== | ==Clinical Features== | ||
*Massive peripheral edema with thickening of overlying skin particularly in lower extremities and genitalia | *Massive peripheral edema with thickening of overlying skin particularly in lower extremities and genitalia | ||
*Recurrent [[cellulitis]] is common | *Recurrent [[cellulitis]] is common | ||
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
== | |||
==Diagnostic Evaluation== | |||
==Management== | ==Management== | ||
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==Disposition== | ==Disposition== | ||
==See Also== | ==See Also== | ||
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==External Links== | ==External Links== | ||
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==References== | |||
<references/> | <references/> | ||
[[Category:ID]] | [[Category:ID]] | ||
[[Category:TropMed]] | [[Category:TropMed]] | ||
Revision as of 09:20, 6 September 2015
Background
- Also known as elephantiasis
- Causative agents:
- Wuchereria bancrofti
- Brugia malayi
- Brugia timori
- Larvae migrate to lymphatic vessels and mature into adults
Clinical Features
- Massive peripheral edema with thickening of overlying skin particularly in lower extremities and genitalia
- Recurrent cellulitis is common
Differential Diagnosis
Diagnostic Evaluation
Management
- Diethylcarbamazine:
- Day 1: 50 mg PO
- Day 2: 50 mg TID
- Day 3: 100 mg TID
- Days 4-21: 6 mg/kg/day divided TID
- Combined treatment with diethylcarbamazine/albendazole or ivermectin/albendazole may be more effective
- Meticulous skin care to prevent superinfection/cellulitis
- Surgical management of scrotal elephantiasis and chronic lymphatic obstruction