IV nitroglycerine alternatives: Difference between revisions

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*Sublingual nitroglycerin, 1-2 tabs or sprays every 5 minutes as needed
*Sublingual nitroglycerin, 1-2 tabs or sprays every 5 minutes as needed
**Once controlled
**Once controlled
***[[Nitropursside]] '''OR''' [[Isordil]] PO (nitro paste or longer acting NTG)
***[[Nitroprusside]] '''OR''' [[Isordil]] PO (nitro paste or longer acting NTG)
**If not well controlled
**If not well controlled
***IV [[enalapril]] 0.625-1.25mg IV bolus
***IV [[enalapril]] 0.625-1.25mg IV bolus

Revision as of 17:51, 3 December 2015

Background

  • Suggestions for substitution during the IV shortage

Nitroglycerine Bioavailability

  • Oral [1]: <1%
  • Sublingual [1]: 38% (15-40%)
  • Topical [1]: 72%

Half-life[2]: 0.05 h

Suggested Substitutions[3]

See Also

References

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