Dialyzable drugs: Difference between revisions
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*Although plasma clearance may be beneficial, increasing plasma clearance will dcrease dialysis clearance. | *Although plasma clearance may be beneficial, increasing plasma clearance will dcrease dialysis clearance. | ||
'''Dialysis Flow Rates''' | '''Dialysis Flow Rates''' | ||
*Greater degrees of dialysis can be achieved with faster dialysate flow rates if the dialysate drug concentrations is low. As the concentration of drug is increased in the diasylate the flow rate needs to be lowered. | |||
==Common Dialyzable Drugs== | ==Common Dialyzable Drugs== | ||
Revision as of 20:52, 6 December 2015
Background
Factors Influencing Dialyzability
Molecular weight
- Smaller molecular weight substances will pass through the dialysis membrane more easily than larger molecular weights.
Protein Binding
- Drugs with a high degree of protein binding will have a small plasma concentration of unbound drug available for dialysis, making them poorly dialyzable or requiring multiple sessions.
Volume of Distribution
- Drugs with large volumes of distribution usually due to lipid solubility and low plasma protein binding are poorly diliazable.
Plasma clearance
- Although plasma clearance may be beneficial, increasing plasma clearance will dcrease dialysis clearance.
Dialysis Flow Rates
- Greater degrees of dialysis can be achieved with faster dialysate flow rates if the dialysate drug concentrations is low. As the concentration of drug is increased in the diasylate the flow rate needs to be lowered.
Common Dialyzable Drugs
- B - Barbiturates
- L - Lithium
- I - Isoniazid
- S - Salicylates
- T - Theophyline/Caffeine (both are methylxanthines)
- M - Methanol
- E - Ethylene glycol
- D - Depakote
- Others - Carbamezepine
Complete dializable drug list[1]
| Drug Name | Conventional Dialysis | High Permeability | Peritoneal Dialysis |
| Amiloride | ND | ND | ND |
| Aminocaproic acid | Yes | ND | Yes |
| Aminoglutethimide | Yes | L | ND |
| Aminosalicylic acid | Yes | L | ND |
| Amiodarone | No | ND | No |
| Amitriptyline | No | ND | No |
| Amlodipine | No | ND | No |
| Amoxapine | U | ND | U |
| Amoxicillin | Yes | L | No |
| Amphotericin B | No | ND | No |
| Ampicillin | Yes | L | No |
| Amprenavir | U | ND | ND |
| Amrinone | U | ND | No |
| Anagrelide | ND | ND | ND |
| Anastrozole | ND | ND | ND |
| Anistreplase | U | ND | U |
| Antithymocyte globulin ATG | U | ND | U |
| Aprotinin | U | ND | U |
| Arbutamine | ND | ND | ND |
| Ardeparin | No | ND | ND |
| Asparaginase | U | ND | U |
| Aspirin | Yes | L | Yes |
| Atenolol | Yes | L | No |
| Atorvastatin | U | ND | U |
| Atovaquone | U | ND | U |
| Atracurium | U | ND | U |
| Atropine | No | ND | ND |
| Auranofin | No | ND | ND |
| Azathioprine | Yes | L | ND |
| Azithromycin | ND | ND | ND |
| Azlocillin | Yes | L | No |
| Aztreonam | Yes | L | No |
| Baclofen | ND | ND | ND |
| Basiliximab | U | ND | U |
| Benazepril (benazeprilat) | No | ND | ND |
| Benzquinamide | U | ND | NA |
| Bepridil | No | ND | U |
| Betamethasone | ND | ND | ND |
| Betaxolol | No | ND | No |
| Bethanechol | ND | ND | ND |
| Bezafibrate | No | ND | No |
| Biapenem | Yes | L | ND |
| Bicalutamide | U | ND | U |
| Bisoprolol | No | ND | ND |
| Bleomycin | No | ND | No |
| Bretylium | Yes | L | ND |
| Bromfenac | No | ND | U |
| Bromocriptine | U | ND | U |
| Buflomedil | No | No | U |
| Bumetanide | No | ND | U |
| Bupropion | No | ND | No |
| Buspirone | No | ND | ND |
| Busulfan | ND | ND | ND |
| Butalbital | ND | ND | ND |
| Butorphanol | U | ND | U |
| Caffeine | ND | ND | ND |
| Calcitriol | No | No | U |
| Candesartan | No | ND | ND |
| Capecitabine | ND | ND | ND |
| Capreomycin | Yes | L | ND |
| Captopril | Yes | L | No |
| Carbamazepine | No | ND | No |
| Carbenicillin | Yes | L | No |
| Carbidopa/levodopa | ND | ND | ND |
| Carboplatin | Yes | L | ND |
| Carboprost | ND | ND | ND |
| Carisoprodol | Yes | L | Yes |
| Carmustine | No | ND | ND |
| Carnitine | Yes | L | ND |
| Carprofen | U | ND | U |
| Carteolol | ND | ND | ND |
| Carumonam | Yes | L | ND |
| Carvedilol | No | ND | ND |
| Cefaclor | Yes | L | Yes |
| Cefadroxil | Yes | L | No |
| Cefamandole | Yes | L | No |
| Cefazolin | Yes | L | No |
| Cefdinir | Yes | L | ND |
| Cefepime | Yes | L | Yes |
| Cefixime | No | ND | No |
| Cefmenoxime | Yes | L | ND |
| Cefmetazole | Yes | L | No |
| Cefodizime | No | ND | No |
| Cefonicid | No | ND | No |
| Cefoperazone | No | ND | No |
| Ceforanide | Yes | L | No |
| Cefotaxime | Yes | L | No |
| Cefotetan | Yes | L | Yes |
| Cefoxitin | Yes | L | No |
| Cefpirome | Yes | Yes | No |
| Cefpodoxime | Yes | L | No |
| Cefprozil | Yes | L | ND |
| Cefroxadine | ND | ND | ND |
| Cefsulodin | Yes | L | Yes |
| Ceftazidime | Yes | L | Yes |
| Ceftibuten | Yes | L | ND |
| Ceftizoxime | Yes | L | No |
| Ceftriaxone | No | ND | No |
| Cefuroxime | Yes | L | No |
| Celecoxib | U | ND | U |
| Cephalexin | Yes | L | No |
| Cephalothin | Yes | L | No |
| Cephapirin | Yes | L | No |
| Cephradine | Yes | L | Yes |
| Cerivastatin | U | ND | U |
| Cetirizine | No | ND | U |
| Chloral Hydrate | Yes | L | ND |
| Chlorambucil | No | ND | No |
| Chloramphenicol | Yes | L | No |
| Chlordiazepoxide | No | ND | U |
| Chloroquine | No | ND | No |
| Chlorpheniramine | Yes | L | No |
| Chlorpromazine | No | ND | No |
| Chlorpropamide | No | ND | No |
| Chlorprothixene | U | ND | U |
| Chlorthalidone | No | ND | U |
| Cidofovir | ND | Yes | No |
| Cilastatin | Yes | L | ND |
| Cilazapril | Yes | L | ND |
| Cilostazol | U | ND | U |
| Cimetidine | No | ND | No |
| Cinoxacin | No | ND | U |
| Ciprofloxacin | No | ND | No |
| Cisapride | No | ND | U |
| Cisatracurium | U | ND | U |
| Cisplatin | No | ND | ND |
| Citalopram | U | ND | U |
| Cladribine | ND | ND | ND |
| Clarithromycin | ND | ND | ND |
| Clavulanic acid | Yes | ND | Yes |
| Clemastine | ND | ND | ND |
| Clindamycin | No | ND | No |
| Clodronate | Yes | ND | No |
| Clofazimine | No | ND | No |
| Clofibrate | No | ND | No |
| Clomipramine | U | ND | U |
| Clonazepam | No | ND | U |
| Clonidine | No | ND | No |
| Clopidogrel | U | ND | U |
| Clorazepate | No | ND | U |
| Cloxacillin | No | ND | No |
| Clozapine | U | ND | U |
| Codeine | No | ND | U |
| Colchicine | No | ND | No |
| Cortisone | No | ND | No |
| Cyclacillin | Yes | L | No |
| Cyclophosphamide | Yes | L | ND |
| Cycloserine | Yes | L | ND |
| Cyclosporine | No | ND | No |
| Cysteamine | ND | ND | No |
| Cytarabine | No | ND | No |
| Dacarbazine | ND | ND | ND |
| Daclizumab | U | ND | U |
| Dactinomycin | ND | ND | ND |
| Dalteparin | U | ND | U |
| Danaparoid | ND | ND | ND |
| Dapsone | Yes | L | ND |
| Daunorubicin | ND | ND | ND |
| Deferoxamine | Yes | L | ND |
| Deflazacort | No | ND | U |
| Delavirdine | U | ND | U |
| Desipramine | No | ND | No |
| Desmopressin | ND | ND | ND |
| Dexamethasone | No | ND | No |
| Dexfenfluramine | ND | ND | ND |
| Dexrazoxane | ND | ND | ND |
| Dezocine | ND | ND | ND |
| Diazepam | No | ND | U |
| Diazoxide | Yes | L | Yes |
| Dibekacin | Yes | L | ND |
| Diclofenac | U | ND | U |
| Dicloxacillin | No | ND | No |
| Didanosine | No | ND | No |
| Diethylpropion | ND | ND | ND |
| Diflunisal | No | ND | U |
| Digitoxin | No | ND | No |
| Digoxin | No | ND | No |
| Dihydroergotamine | ND | ND | ND |
| Diltiazem | No | ND | No |
| Diphenhydramine | U | ND | U |
| Diphenoxylate/Atropine | ND | ND | ND |
| Dipyridamole | U | ND | ND |
| Dirithromycin | No | ND | No |
| Disopyramide | Yes | L | ND |
| Dobutamine | No | ND | No |
| Docetaxel | U | ND | U |
| Dolasetron | ND | ND | ND |
| Donepezil | U | ND | U |
| Dopamine | No | ND | U |
| Doxacurium | No | ND | U |
| Doxazosin | No | ND | No |
| Doxepin | No | ND | No |
| Doxercalciferol | No | ND | U |
| Doxorubicin | No | ND | ND |
| Doxycycline | No | ND | No |
| Dronabinol | U | ND | U |
| Droperidol | U | ND | U |
| Edetate calcium (EDTA) | Yes | L | Yes |
| Efavirenz | U | ND | U |
| Enalapril (enalaprilat) | Yes | L | Yes |
| Encainide | No | ND | ND |
| Enoxacin | No | ND | No |
| Enoxaparin | No | ND | U |
| Ephedrine | ND | ND | ND |
| Epinephrine | ND | ND | ND |
| Epoetin alfa | No | ND | No |
| Epoprostenol | ND | ND | ND |
| Eprosartan | U | No | U |
| Eptifibatide | ND | ND | ND |
| Ergocalciferol | ND | ND | ND |
| Erythromycin | No | ND | No |
| Esmolol (ASL-8123) | Yes | L | Yes |
| Estazolam | U | ND | U |
| Ethacrynic acid | No | ND | U |
| Ethambutol | No | No | U |
| Ethchlorvynol | No | ND | No |
| Ethinyl estradiol | ND | ND | No |
| Ethosuximide | Yes | L | ND |
| Etodolac | No | ND | U |
| Etoposide | No | ND | No |
| Famciclovir (penciclovir) | Yes | L | ND |
| Famotidine | No | ND | No |
| Felbamate | ND | ND | ND |
| Felodipine | No | ND | U |
| Fenfluramine | ND | ND | ND |
| Fenofibrate | No | ND | U |
| Fenoldopam | U | ND | No |
| Fenoprofen | No | ND | U |
| Fentanyl | ND | ND | ND |
| Ferric gluconate | No | ND | U |
| Ferrous (iron) salts | U | ND | U |
| Fexofenadine | No | ND | U |
| Filgrastim | No | ND | U |
| Finasteride | U | ND | U |
| Flecainide | No | ND | U |
| Fleroxacin | No | No | No |
| Floxuridine | ND | ND | ND |
| Fluconazole | Yes | L | Yesa |
| Flucytosine | Yes | L | Yes |
| Fludarabine | ND | ND | ND |
| Flumazenil | ND | ND | ND |
| Fluorouracil | Yes | L | ND |
| Fluoxetine | No | ND | No |
| Fluphenazine | U | ND | U |
| Flurazepam | No | ND | U |
| Flurbiprofen | ND | ND | No |
| Flutamide | No | ND | U |
| Fluvastatin | U | ND | U |
| Fluvoxamine | U | ND | U |
| Fomepizole | Yes | L | ND |
| Foscarnet | Yes | Yes | ND |
| Fosfomycin | Yes | L | ND |
| Fosinopril (fosinoprilat) | No | ND | No |
| Fosphenytoin | U | ND | U |
| Furosemide | No | ND | U |
| Fusidic acid | No | ND | No |
| Gabapentin | Yes | L | ND |
| Gadodiamide | Yes | L | No |
| Gadoversetamide | ND | Yes | ND |
| Gallium | ND | ND | ND |
| Gallopamil | U | ND | U |
| Ganciclovir | Yes | L | ND |
| Ganirelix | ND | ND | ND |
| Gemcitabine | ND | ND | ND |
| Gemfibrozil | No | ND | No |
| Gentamicin | Yes | Yes | Yes |
| Glatiramer | ND | ND | ND |
| Glimepiride | U | ND | U |
| Glipizide | U | ND | U |
| Glucagon | U | ND | U |
| Glutethimide | No | ND | No |
| Glyburide | No | ND | U |
| Gold sodium thiomalate | No | ND | U |
| Granisetron | ND | ND | ND |
| Grepafloxacin | ND | ND | ND |
| Guanabenz | U | ND | ND |
| Guanadrel | ND | ND | ND |
| Guanethidine | ND | ND | ND |
| Guanfacine | No | ND | No |
| Halofantrine | ND | ND | ND |
| Haloperidol | No | ND | No |
| Heparin | No | ND | No |
| Hexobarbital | No | ND | U |
| Hirudin | No | No | ND |
| Hydralazine | No | ND | No |
| Hydrochlorothiazide | No | ND | U |
| Hydrocodone | ND | ND | ND |
| Hydrocortisone | U | ND | U |
| Hydromorphone | ND | ND | ND |
| Hydroxychloroquine | ND | ND | ND |
| Hydroxyurea | No | ND | U |
| Hydroxyzine | No | ND | No |
| Ibuprofen | No | ND | U |
| Ibutilide | ND | ND | ND |
| Idarubicin | U | ND | U |
| Ifosfamide | Yes | L | ND |
| Imipenem | Yes | L | Yes |
| Imipramine | No | ND | No |
| Immune globulin(human) | U | ND | U |
| Indapamide | No | ND | U |
| Indinavir | ND | ND | ND |
| Indomethacin | No | ND | U |
| Insulin | No | ND | No |
| Interferons | No | ND | No |
| Iodixanol | Yes | L | ND |
| Iopromide | Yes | Yes | ND |
| Irbesartan | No | ND | ND |
| Irinotecan (SN-38 metabolite) | U | ND | U |
| Iron dextran | No | ND | U |
| Isocarboxazid | ND | ND | ND |
| Isoniazid | No | No | U |
| Isoproterenol | ND | ND | ND |
| Isosorbide dinitrate | No | ND | No |
| Isosorbide mononitrate | Yes | L | No |
| Isradipine | No | ND | No |
| Itraconazole | No | ND | U |
| Kanamycin | Yes | L | Yes |
| Ketoconazole | No | ND | No |
| Ketoprofen | U | ND | U |
| Ketorolac | U | ND | U |
| Labetalol | No | ND | No |
| Lamivudine | No | ND | U |
| Lamotrigine | No | ND | U |
| Lansoprazole | No | ND | U |
| Leflunomide | No | ND | No |
| Letrozole | ND | ND | ND |
| Leuprolide | ND | ND | ND |
| Levamisole | ND | ND | ND |
| Levobupivacaine | U | ND | U |
| Levofloxacin | U | ND | U |
| Levonorgestrel | U | ND | U |
| Levorphanol | ND | ND | ND |
| Levothyroxine | U | ND | U |
| Lidocaine | No | ND | U |
| Lincomycin | No | ND | No |
| Lisinopril | Yes | L | ND |
| Lithium | Yes | L | Yes |
| Lomefloxacin | No | ND | No |
| Lomustine | No | ND | U |
| Loperamide | ND | ND | ND |
| Loracarbef | Yes | L | ND |
| Loratadine | No | ND | No |
| Lorazepam | No | ND | U |
| Losartan | No | ND | No |
| Lovastatin | U | ND | U |
| Loxapine | ND | ND | ND |
| Mangafodipir | ND | ND | ND |
| Mannitol | Yes | L | Yes |
| Maprotiline | No | ND | U |
| Mechlorethamine | No | ND | No |
| Meclofenamate | U | ND | U |
| Mefenamic acid | No | ND | U |
| Mefloquine | U | ND | U |
| Melphalan | No | ND | ND |
| Meperidine | No | ND | U |
| Meprobamate | Yes | L | Yes |
| Mercaptopurine | Yes | L | ND |
| Meropenem | Yes | L | ND |
| Mesalamine (5-ASA) | U | ND | U |
| Mesna | ND | ND | ND |
| Mesoridazine | U | ND | U |
| Metaproterenol | ND | ND | ND |
| Metformin | Yes | L | ND |
| Methadone | No | ND | No |
| Methaqualone | No | ND | No |
| Methenamine | ND | ND | ND |
| Methicillin | No | ND | No |
| Methimazole | No | ND | No |
| Methotrexate | Yes | Yes | No |
| Methyldopa | Yes | L | Yes |
| Methylphenidate | U | ND | U |
| Methylprednisolone | Yes | L | ND |
| Metoclopramide | No | ND | No |
| Metolazone | No | ND | U |
| Metoprolol | Yes | L | ND |
| Metronidazole | Yes | L | No |
| Mexiletine | Yes | L | No |
| Mezlocillin | Yes | L | No |
| Miacalcin | ND | ND | ND |
| Miconazole | No | ND | No |
| Midazolam | No | ND | U |
| Midodrine (de-glymidodrine) | Yes | ND | NA |
| Miglitol | ND | ND | ND |
| Milrinone | ND | ND | ND |
| Minocycline | No | ND | No |
| Minoxidil | Yes | L | Yes |
| Mirtazapine | U | ND | U |
| Misoprostol | U | ND | U |
| Mitomycin | ND | ND | ND |
| Mitoxantrone | No | ND | No |
| Mivacurium | ND | ND | ND |
| Modafinil | ND | ND | ND |
| Moexipril | ND | ND | ND |
| Molindone | U | ND | U |
| Montelukast | U | ND | U |
| Moricizine | U | ND | U |
| Morphine | Yes | ND | No |
| Muromonab-CD3 | U | ND | U |
| Mycophenolate (mycophenolic acid) | No | ND | No |
| Nabumetone | No | ND | ND |
| Nadolol | Yes | L | ND |
| Nafcillin | No | ND | No |
| Nalmefene | No | ND | U |
| Naloxone | ND | ND | ND |
| Naltrexone | ND | ND | ND |
| Naproxen | No | ND | U |
| Naratriptan | ND | ND | ND |
| Nefazodone | U | ND | U |
| Nelfinavir | U | ND | U |
| Netilmicin | Yes | L | Yes |
| Nevirapine | ND | ND | ND |
| Nicardipine | No | ND | U |
| Nicotine | ND | ND | ND |
| Nicotinic acid | ND | ND | ND |
| Nifedipine | No | ND | No |
| Nilutamide | ND | ND | ND |
| Nimodipine | No | ND | No |
| Nisoldipine | No | ND | No |
| Nitrendipine | No | ND | U |
| Nitrofurantoin | Yes | L | ND |
| Nitroglycerin | No | ND | No |
| Nitroprusside | Yes | L | Yes |
| Nizatidine | No | ND | No |
| Nomifensine | ND | ND | ND |
| Norethindrone | ND | ND | No |
| Norfloxacin | No | ND | U |
| Nortriptyline | No | ND | No |
| Octreotide | Yes | L | ND |
| Ofloxacin | Yes | ND | No |
| Olanzapine | No | ND | No |
| Olsalazine | U | ND | U |
| Omapatrilat | No | ND | ND |
| Omeprazole | U | ND | U |
| Ondansetron | U | ND | U |
| Orbofiban | Yes | L | ND |
| Orlistat | U | ND | U |
| Ornidazole | Yes | L | No |
| Orphenadrine | ND | ND | ND |
| Oxacillin | No | ND | No |
| Oxaprozin | No | ND | U |
| Oxazepam | No | ND | U |
| Oxybutynin | ND | ND | ND |
| Oxycodone | ND | ND | ND |
| Oxymorphone | ND | ND | ND |
| Paclitaxel | No | ND | U |
| Pamidronate | ND | ND | ND |
| Pancuronium | ND | ND | ND |
| Pantoprazole | No | ND | ND |
| Paricalcitol | No | ND | ND |
| Paroxetine | No | ND | U |
| Pefloxacin | No | ND | No |
| Pegaspargase | U | ND | U |
| Pemoline | Yes | L | No |
| Penbutolol | No | ND | No |
| Penicillamine | Yes | L | ND |
| Pencillin G | Yes | L | No |
| Pentamidine | No | ND | No |
| Pentazocine | Yes | L | ND |
| Pentobarbital | No | ND | U |
| Pentosan polysulfate | ND | ND | ND |
| Pentostatin | ND | ND | ND |
| Pentoxifylline | U | ND | ND |
| Pergolide | U | ND | U |
| Perindopril (perindoprilat) | Yes | L | ND |
| Perphenazine | U | ND | U |
| Phenelzine | ND | ND | ND |
| Phenobarbital | Yes | L | Yes |
| Phentermine | ND | ND | ND |
| Phentolamine | ND | ND | ND |
| Phenylbutazone | No | ND | U |
| Phenylpropanolamine | ND | ND | ND |
| Phenytoin | No | Yes | No |
| Pimagedine (aminoguanidine) | Yes | ND | ND |
| Pimozide | ND | ND | ND |
| Pindolol | ND | ND | ND |
| Pioglitazone | U | ND | U |
| Piperacillin | Yes | L | No |
| Piroxicam | U | ND | U |
| Plicamycin | ND | ND | ND |
| Polythiazide | No | ND | No |
| Pralidoxime | ND | ND | ND |
| Pramipexole | No | ND | U |
| Pravastatin | No | ND | ND |
| Prazepam | No | ND | U |
| Prazosin | No | ND | No |
| Prednisone | No | ND | No |
| Primidone | Yes | L | ND |
| Probucol | No | ND | No |
| Procainamide | Yes | L | No |
| Procarbazine | ND | ND | ND |
| Prochlorperazine | U | ND | U |
| Promazine | U | ND | U |
| Promethazine | No | ND | ND |
| Propafenone | No | ND | No |
| Propofol | U | ND | U |
| Propoxyphene | No | ND | No |
| Propranolol | No | ND | No |
| Protriptyline | No | ND | No |
| Pseudoephedrine | No | ND | U |
| Pyrazinamide | Yes | Yes | No |
| Pyrimethamine | ND | ND | ND |
| Quazepam | U | ND | U |
| Quetiapine | ND | ND | ND |
| Quinapril (quinaprilat) | No | ND | No |
| Quinidine | No | ND | No |
| Quinine | No | ND | No |
| Quinupristin/dalfopristin | ND | ND | No |
| Rabeprazole | U | ND | U |
| Raloxifene | U | ND | U |
| Ramipril (ramiprilat) | No | ND | ND |
| Ranitidine | No | ND | No |
| Recainam | No | ND | U |
| Repaglinide | U | ND | U |
| Reserpine | No | ND | No |
| Reteplase | ND | ND | ND |
| Reviparin | No | ND | U |
| Rifabutin | U | ND | U |
| Rifampin | No | No | No |
| Rifapentine | U | ND | U |
| Rilmenidine | No | ND | U |
| Rimantadine | No | ND | U |
| Risperidone | ND | ND | ND |
| Ritodrine | Yes | L | Yes |
| Ritonavir | U | ND | U |
| Rizatriptan | ND | ND | ND |
| Rocuronium | ND | ND | ND |
| Rofecoxib | No | ND | U |
| Ropinirole | U | ND | U |
| Rosiglitazone | No | ND | U |
| Roxithromycin | ND | ND | No |
| Rufloxacin | ND | ND | ND |
| Salsalate | Yes | L | No |
| Saquinavir | U | ND | U |
| Sargramostim | ND | ND | ND |
| Secobarbital | No | ND | No |
| Selegiline | ND | ND | ND |
| Sermorelin | ND | ND | ND |
| Sertindole | No | ND | ND |
| Sertraline | No | ND | U |
| Sevelamer | U | U | U |
| Sibutramine | U | ND | U |
| Sildenafil | U | ND | U |
| Silver | No | ND | U |
| Simvastatin | U | ND | U |
| Sirolimus | U | ND | ND |
| Sisomicin | Yes | L | ND |
| Somatropin | U | ND | U |
| Sotalol | Yes | L | ND |
| Sparfloxacin | ND | ND | ND |
| Spectinomycin | Yes | L | Yes |
| Spirapril (spiraprilat) | U | ND | U |
| Spironolactone | U | ND | U |
| Stavudine | ND | ND | ND |
| Streptomycin | Yes | L | Yes |
| Streptozocin | ND | ND | ND |
| Sucralfate | No | ND | No |
| Sufentanil | U | ND | U |
| Sulbactam | Yes | L | No |
| Sulfamethoxazole | Yes | L | No |
| Sulfisoxazole | Yes | L | Yes |
| Sulindac | No | ND | U |
| Sumatriptan | ND | ND | ND |
| Tacrine | ND | ND | ND |
| Tacrolimus | No | ND | U |
| Tamoxifen | ND | ND | ND |
| Tamsulosin | U | ND | U |
| Tazobactam | Yes | L | No |
| Teicoplanin | No | ND | No |
| Telmisartan | U | ND | U |
| Temazepam | No | ND | U |
| Temocillin | Yes | L | No |
| Teniposide | U | ND | U |
| Terazosin | No | ND | No |
| Terbinafine | U | ND | U |
| Terbutaline | ND | ND | ND |
| Testosterone | U | ND | U |
| Tetracycline | No | ND | No |
| Thalidomide | ND | ND | ND |
| Theophylline | Yes | L | No |
| Thiethylperazine | ND | ND | ND |
| Thioguanine | ND | ND | ND |
| Thioridazine | U | ND | U |
| Thiotepa | ND | ND | ND |
| Thiothixene | U | ND | U |
| Tiagabine | No | ND | ND |
| Ticarcillin | Yes | L | No |
| Ticlopidine | U | ND | U |
| Tiludronate | U | ND | U |
| Timolol | No | ND | No |
| Tinidazole | Yes | L | ND |
| Tirofiban | Yes | L | ND |
| Tizanidine | ND | ND | ND |
| Tobramycin | Yes | L | Yes |
| Tocainide | Yes | L | ND |
| Tolazamide | U | ND | U |
| Tolbutamide | No | ND | U |
| Tolcapone | U | ND | ND |
| Tolmetin | U | ND | U |
| Tolterodine | U | ND | U |
| Topiramate | Yes | L | ND |
| Topotecan | ND | ND | ND |
| Torsemide | No | ND | U |
| Tramadol | No | ND | U |
| Trandolapril (trandolaprilat) | Yes | L | ND |
| Tranexamic acid | ND | ND | ND |
| Tranylcypromine | ND | ND | ND |
| Trapidil | ND | ND | ND |
| Trazodone | U | ND | U |
| Tretinoin | ND | ND | ND |
| Triamterene | ND | ND | ND |
| Triazolam | No | ND | U |
| Trifluoperazine | No | ND | No |
| Triflupromazine | U | ND | U |
| Trihexyphenidyl | ND | ND | ND |
| Trimethoprim | Yes | L | No |
| Trimetrexate | U | ND | U |
| Trimipramine | U | ND | U |
| Troglitazone | U | ND | U |
| Tropisetron | U | ND | U |
| Trovafloxacin | No | ND | ND |
| Ursodiol | U | ND | U |
| Valacyclovir | Yes | L | ND |
| Valproic acid | No | ND | No |
| Valsartan | U | ND | U |
| Vancomycin | No | Yes | No |
| Vecuronium | U | ND | U |
| Venlafaxine | No | ND | U |
| Verapamil | No | ND | No |
| Vigabatrin | Yes | L | ND |
| Vinblastine | ND | ND | ND |
| Vincristine | ND | ND | ND |
| Warfarin | No | ND | No |
| Zafirlukast | U | ND | U |
| Zalcitabine | ND | ND | ND |
| Zidovudine/GZDV | No/Yes | ND/L | No/Yes |
| Zileuton | No | ND | U |
| Zolmitriptan | ND | ND | ND |
| Zolpidem | No | ND | U |
Yes- dialyzable, No-not dialyzable, U-unlikely, L-likely but no data, ND-no data, NS- no high permeability membrane specified
See Also
References
- ↑ Dialysis of Drugs. Nephrology Pharmacy Associates. 2000.