Gyromitra mushrooms: Difference between revisions
GregArmani (talk | contribs) No edit summary |
GregArmani (talk | contribs) No edit summary |
||
| Line 21: | Line 21: | ||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Tox]] | |||
Revision as of 01:53, 11 January 2016
Overview
- Also known as "brain fungi"
- Fruit in the spring and early summer
- Frequently mistaken for morel mushrooms[1]
- Inhibits formation of Vitamin B6 and GABA via hydrazine metabolite
Clinical findings
- GI upset, fatigue, muscle cramps
- Can present with refractory seizures due to GABA deficiency
- Hemolysis usually mild
- Rarely methemoglobinemia
Treatment
- Supportive care
- High dose pyridoxine for refractory seizures (5g IV initially)
- Avoid phenobarbital, especially in liver failure
- Methylene blue for severe methemoglobinemia
- Folinic acid supplementation (hydrazines inhibit MTHF production)
References
- ↑ Brozen R et al. Gyromitra Mushroom Toxicity. Apr 14, 2015. http://emedicine.medscape.com/article/817931-treatment#showall.